Characterization of HEPG2 cells behavior in critical frequency domain on tiopc-based optoelectronic dielectrophoresis chip

Shih Mo Yang*, Chun Yen Lin, Shilpa Sivashankar, Srinivasu Valagerahally Puttaswamy, Sung Yang Wei, Tung Ming Yu, Hwan You Chang, Long Hsu, Cheng Hsien Liu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

In this article we categorize frequency dependent behaviors of HepG2 cell on TiOPc-based optoelectronic dielectrophoresis chip. Previous works of optoelectronic manipulation only focus on positive or negative dielectrophoresis effect of cell manipulation. Our cell behavior calibration fills the blank of frequency domain between positive and negative dielectrophoresis on TiOPc-coated substrate. Besides, the careful investigation of critical frequency would apply to separate and select high and low permeable membrane cells. Finally, utilizing atomic force microscope to measure the TiOPc-coated surface roughness, determining cell viability on TiOPc surface for 168 hrs, and applying negative dielectrophoresis force to arrange cells array provides deeper knowledge for this organic photoconductive material application.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages1900-1902
Number of pages3
StatePublished - 1 Dec 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2 Oct 20116 Oct 2011

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume3

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Country/TerritoryUnited States
CitySeattle, WA
Period2/10/116/10/11

Keywords

  • Cell culture
  • Cell manipulation
  • Optoelectronic dielectrophoresis
  • Organic ohotoconductivity

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