Characteristics and significance of very early recurrence of atrial fibrillation after catheter ablation

Shih Lin Chang, Hsuan Ming Tsao, Yenn Jiang Lin, Li Wei Lo, Yu Feng Hu, Ta Chuan Tuan, Kazuyoshi Suenari, Ching Tai Tai, Cheng Hung Li, Tze Fan Chao, Yung Kuo Lin, Chin Feng Tsai, Tsu Juey Wu, Shih Ann Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Very Early Recurrence of AF. Introduction: Early restoration of sinus rhythm following ablation of atrial fibrillation (AF) facilitates reverse atrial remodeling and improves the long-term outcome. The purpose of this study was to determine the predictors and outcome in patients with very early AF recurrences (< 2 days). Methods and Results: Ablation was performed in 339 consecutive AF patients (paroxysmal AF = 262). Biatrial voltage was mapped during sinus rhythm. If recurrent AF occurred within 2 days following the ablation, electrical cardioversion was performed to restore sinus rhythm. Very early recurrences of AF occurred in 39 (15%) patients with paroxysmal AF and 26 (34%) with nonparoxysmal AF. Patients with very early recurrence had a higher incidence of nonparoxysmal AF (40% vs 18.6%, P< 0.001), requirement of electrical cardioversion during procedure, larger left atrial (LA) diameter (43 ± 7 vs 39 ± 6 mm, P< 0.001), lower left ventricular ejection fraction (54 ± 10% vs 59 ± 7, P< 0.001), longer procedural time, and lower LA voltage (1.5 ± 0.7 vs 1.9 ± 0.8 mV, P< 0.001). A multivariate analysis revealed that the independent predictors of a very early recurrence were a longer procedural time and lower LA voltage. During a follow-up of 13 ± 5 months, a very early recurrence did not predict the long-term outcome of a single procedure recurrence in the patients with paroxysmal AF, but was associated with a late recurrence in the nonparoxysmal AF patients. Conclusion: Very early recurrence occurred in patients with paroxysmal AF is not associated with long-term recurrence. Nonparoxysmal AF is an independent predictor of late recurrence of AF in patients with very early recurrence.

Original languageEnglish
Pages (from-to)1193-1198
Number of pages6
JournalJournal of cardiovascular electrophysiology
Issue number11
StatePublished - Nov 2011


  • atrial fibrillation
  • cardioversion
  • catheter ablation
  • electroanatomic mapping
  • pulmonary vein isolation


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