CHADS 2 and CHA 2DS 2-VASc scores in the prediction of clinical outcomes in patients with atrial fibrillation after catheter ablation

Tze Fan Chao, Yenn Jiang Lin, Hsuan Ming Tsao, Chin Feng Tsai, Wei Shiang Lin, Shih Lin Chang, Li Wei Lo, Yu Feng Hu, Ta Chuan Tuan, Kazuyoshi Suenari, Cheng Hung Li, Beny Hartono, Hung Yu Chang, Kibos Ambrose, Tsu Juey Wu, Shih Ann Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

156 Scopus citations

Abstract

Objectives: This study aimed to evaluate whether CHADS 2 and CHA 2DS 2-VASc scores are useful for risk stratification in patients after catheter ablation of atrial fibrillation (AF). Background: AF is associated with increased risk of cardiovascular events. However, limited data are available on the predictors of adverse events in patients with AF after catheter ablation. Methods: A total of 565 patients with AF who underwent catheter ablation were enrolled in the study. The clinical endpoint was occurrence of thromboembolic events (ischemic stroke, transient ischemic attack, peripheral embolism, or pulmonary embolisms) or death during follow-up after catheter ablation. Results: During a follow-up of 39.2 ± 22.6 months, 27 patients (4.8%) experienced adverse events. Both the CHADS 2 and CHA 2DS 2-VASc scores were useful predictors of events in separate multivariate models. The areas under the receiver-operator characteristic curves based on the CHADS 2 and CHA 2DS 2-VASc scores in predicting events were 0.785 and 0.830, respectively. Although the difference did not reach statistical significance (p = 0.116), the CHA 2DS 2-VASc score could be used to further stratify the patients with CHADS 2 scores of 0 or 1 into 2 groups with different event rates (7.1% vs. 1.1%, p = 0.003) at a cutoff value of 2. Conclusions: The CHADS 2 and CHA 2DS 2-VASc scores are useful predictors of adverse events after catheter ablation of AF.

Original languageEnglish
Pages (from-to)2380-2385
Number of pages6
JournalJournal of the American College of Cardiology
Volume58
Issue number23
DOIs
StatePublished - 29 Nov 2011

Keywords

  • CHA DS -VASc score
  • CHADS score
  • atrial fibrillation
  • catheter ablation

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