Catheter ablation of paroxysmal atrial fibrillation originating from non-pulmonary vein areas

Satoshi Higa, Li Wei Lo, Shih Ann Chen*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Pulmonary veins (PVs) are a major source of ectopic beats that initiate AF. PV isolation from the left atrium is an effective therapy for the majority of paroxysmal AF. However, investigators have reported that ectopy originating from non-PV areas can also initiate AF. Patients with recurrent AF after persistent PV isolation highlight the need to identify non-PV ectopy. Furthermore, adding non-PV ablation after multiple AF ablation procedures leads to lower AF recurrence and a higher AF cure rate. These findings suggest that non-PV ectopy is important in both the initiation and recurrence of AF. This article summarises current knowledge about the electrophysiological characteristics of non-PV AF, suitable mapping and ablation strategies, and the safety and efficacy of catheter ablation of AF initiated by ectopic foci originating from non-PV areas.

Original languageEnglish
Pages (from-to)273-281
Number of pages9
JournalArrhythmia and Electrophysiology Review
Issue number4
StatePublished - 1 Dec 2018


  • Atrial fibrillation
  • Catheter ablation
  • Non-pulmonary vein
  • Trigger


Dive into the research topics of 'Catheter ablation of paroxysmal atrial fibrillation originating from non-pulmonary vein areas'. Together they form a unique fingerprint.

Cite this