TY - JOUR
T1 - Carbon-based materials for photo-triggered theranostic applications
AU - Albert, Karunya
AU - Hsu, Hsin-Yun
PY - 2016/11/20
Y1 - 2016/11/20
N2 - Carbon-based nanomaterials serve as a type of smart material for photo-triggered disease theranostics. The inherent physicochemical properties of these nanomaterials facilitate their use for less invasive treatments. This review summarizes the properties and applications of materials including fullerene, nanotubes, nanohorns, nanodots and nanographenes for photodynamic nanomedicine in cancer and antimicrobial therapies. Carbon nanomaterials themselves do not usually act as photodynamic therapy (PDT) agents owing to the high hydrophobicity, however, when the surface is passivated or functionalized, these materials become great vehicles for PDT. Moreover, conjugation of carbonaceous nanomaterials with the photosensitizer (PS) and relevant targeting ligands enhances properties such as selectivity, stability, and high quantum yield, making them readily available for versatile biomedical applications.
AB - Carbon-based nanomaterials serve as a type of smart material for photo-triggered disease theranostics. The inherent physicochemical properties of these nanomaterials facilitate their use for less invasive treatments. This review summarizes the properties and applications of materials including fullerene, nanotubes, nanohorns, nanodots and nanographenes for photodynamic nanomedicine in cancer and antimicrobial therapies. Carbon nanomaterials themselves do not usually act as photodynamic therapy (PDT) agents owing to the high hydrophobicity, however, when the surface is passivated or functionalized, these materials become great vehicles for PDT. Moreover, conjugation of carbonaceous nanomaterials with the photosensitizer (PS) and relevant targeting ligands enhances properties such as selectivity, stability, and high quantum yield, making them readily available for versatile biomedical applications.
KW - Carbon materials
KW - Nanomedicine
KW - Near infrared-triggered agents
KW - Photodynamic therapy
KW - Photosensitizer
UR - http://www.scopus.com/inward/record.url?scp=84997667013&partnerID=8YFLogxK
U2 - 10.3390/molecules21111585
DO - 10.3390/molecules21111585
M3 - Review article
C2 - 27879628
AN - SCOPUS:84997667013
SN - 1420-3049
VL - 21
JO - Molecules
JF - Molecules
IS - 11
M1 - 1585
ER -