Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data

Yuan Hsi Tseng, Chien Wei Chen, Min Yi Wong, Teng Yao Yang, Yu Hui Lin, Bor Shyh Lin, Yao Kuang Huang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The progression of clinical manifestations of lower-limb varicose veins remains unclear. This study investigated changes in lower-limb venous blood flow using phase-contrast magnetic resonance angiography. Data were collected on veins from 141 legs. We compared legs with and without varicose veins and related symptoms and examined varying levels of varicose vein symptom severity. Legs without varicose veins exhibited a lower absolute stroke volume (ASV, p<0.01) and mean flux (MF, p=0.03) for the great saphenous vein (GSV) compared with legs with symptomatic varicose veins. Legs with asymptomatic varicose veins exhibited lower MF for the GSV (p = 0.02) compared with legs with symptomatic varicose veins. Among legs with varicose veins, asymptomatic legs exhibited lower ASV (p=0.03) and MF (p=0.046) for the GSV compared with legs that exhibited skin changes or ulcers; however, no significant differences were observed between legs presenting with discomfort or edema and legs with skin changes or ulcers, and between legs presenting with discomfort or edema and asymptomatic legs. In conclusion, in the supine position, increased blood flow rate and blood flow volume in the GSV were associated with symptomatic varicose veins and increased symptom severity.

Original languageEnglish
Article number118
JournalDiagnostics
Volume12
Issue number1
DOIs
StatePublished - Jan 2022

Keywords

  • Great saphenous vein
  • Magnetic resonance imaging
  • Magnetic resonance venography
  • Non-contrast venography
  • Phase-contrast magnetic resonance imaging
  • Quantitative flow
  • Varicose vein

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