Biomechanical analysis and design method for patient-specific reconstructive implants for large bone defects of the distal lateral femur

Po Kuei Wu, Cheng Wei Lee, Wei Hsiang Sun, Chun Li Lin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This study aims to develop a generalizable method for designing a patient-specific recon-structive scaffold implant for a large distal lateral femur defect using finite element (FE) analysis and topology optimization. A 3D solid-core implant for the distal femur defect was designed to withhold the femur load. Data from FE analysis of the solid implant were use for topology optimization to obtain a ‘bone scaffold implant’ with light-weight internal cavity and surface lattice features to allow for filling with bone material. The bone scaffold implant weighed 69.6% less than the original solid-core implant. The results of FE simulation show that the bone repaired with the bone scaffold implant had lower total displacement (12%), bone plate von Mises stress (34%), bone maximum first principal stress (33%), and bone maximum first principal strain (32%) than did bone repaired with bone cement. The trend in experimental strain with increasing load on the composite femur was greater with bone cement than with the bone scaffold implant. This study presents a generalizable method for designing a patient-specific reconstructive scaffold implant for the distal lateral femur defect that has sufficient strength and space for filling with allograft bone.

Original languageEnglish
Article number4
JournalBiosensors
Volume12
Issue number1
DOIs
StatePublished - Jan 2022

Keywords

  • 3D printing
  • Bone cement
  • Finite element analysis
  • Patient-specific implant
  • Topology optimization

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