Bio-impedance measurement optimization for high-resolution carotid pulse sensing

Ting Wei Wang, Hsiao Wei Chu, Lin Chou, Yen Ling Sung, Yuan Ta Shih, Po Chun Hsu, Hao Min Cheng, Shien Fong Lin*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review


    Continuous hemodynamic monitoring is important for long-term cardiovascular healthcare, especially in hypertension. The impedance plethysmography (IPG) based carotid pulse sensing is a non-invasive diagnosis technique for measuring pulse signals and further evaluating the arterial conditions of the patient such as continuous blood pressure (BP) monitoring. To reach the high-resolution IPG-based carotid pulse detection for cardiovascular applications, this study provides an optimized measurement parameter in response to obvious pulsation from the carotid artery. The influence of the frequency of excitation current, electrode cross-sectional area, electrode arrangements, and physiological site of carotid arteries on IPG measurement resolution was thoroughly investigated for optimized parameters. In this study, the IPG system was implemented and installed on the subject’s neck above the carotid artery to evaluate the measurement parameters. The measurement results within 6 subjects obtained the arterial impedance variation of 2137 mΩ using the optimized measurement conditions, including excitation frequency of 50 kHz, a smaller area of 2 cm2, electrode spacing of 4 cm and 1.7 cm for excitation and sensing functions, and location on the left side of the neck. The significance of this study demonstrates an optimized measurement methodology of IPG-based carotid pulse sensing that greatly improves the measurement quality in cardiovascular monitoring.

    Original languageEnglish
    Article number1600
    Pages (from-to)1-13
    Number of pages13
    Issue number5
    StatePublished - 1 Mar 2021


    • Bio-impedance measurement
    • Cardiovascular monitoring
    • Carotid pulse sensing
    • Continuous blood pressure
    • Hemodynamics
    • Impedance plethysmography (IPG)


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