Bilateral neurotrophic keratopathy complicating vidian neurectomy

Pei Yu Lin*, Ching Yu Cheng, Chih Chiou Wu, May Yung Yen, Shuu Jiun Wang, Kwong Kum Liao, Shui Mei Lee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


PURPOSE: To present a case of bilateral neurotrophic keratopathy with miosis after bilateral Vidian neurectomy for vasomotor rhinitis. METHODS: Observational case report. RESULTS: A 68 year-old man presented with irritation and blurred vision in both eyes 2 weeks after bilateral Vidian neurectomy. Slit-lamp examination revealed a large epithelial defect, typical of neurotrophic keratopathy, in the inferior two-thirds of cornea in both eyes. Corneal sensitivity test with a Cochet-Bonnet anesthesiometer and electrical study of the blink reflex indicated bilateral trigeminal dysfunction. Both pupils were miotic, and tests with hydroxyamphetamine 1% and epinephrine 0.1% showed postganglionic sympathetic nerve damage. The corneal epithelial defects healed after 2 months of treatment with systemic prednisolone, vitamin B12 and tarsorrhaphy. CONCLUSION: Neurotrophic keratopathy associated with dry eye syndrome may be a serious complication of Vidian neurectomy.

Original languageEnglish
Pages (from-to)106-108
Number of pages3
JournalAmerican Journal of Ophthalmology
Issue number1
StatePublished - 2001


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