Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection

Jessica Liu; Hui Han Hu; Chia Ling Chang; Chin Lan Jen; Mei Hsuan Lee; Sheng Nan Lu; Li Yu Wang; Quan Yuan; Ning Shao Xia; Masaya Sugiyama; Nao Nishida; Masashi Mizokami; Chien Jen Chen; Pei Jer Chen; Hwai I. Yang

doi:10.1016/j.cgh.2018.09.037

Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection

Jessica Liu, Hui Han Hu, Chia Ling Chang, Chin Lan Jen, Mei Hsuan Lee, Sheng Nan Lu, Li Yu Wang, Quan Yuan, Ning Shao Xia, Masaya Sugiyama, Nao Nishida, Masashi Mizokami, Chien Jen Chen, Pei Jer Chen, Hwai I. Yang^*

^*Corresponding author for this work

Institute of Clinical Medicine

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).¹ Predictors of HBeAg seroclearance include lower HBV DNA levels, viral genotype, the precore mutation, and higher serum alanine aminotransferase (ALT) levels.²

Original language	English
Pages (from-to)	1413-1415
Number of pages	3
Journal	Clinical Gastroenterology and Hepatology
Volume	17
Issue number	7
DOIs	https://doi.org/10.1016/j.cgh.2018.09.037
State	Published - Jun 2019

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10.1016/j.cgh.2018.09.037

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Liu, J., Hu, H. H., Chang, C. L., Jen, C. L., Lee, M. H., Lu, S. N., Wang, L. Y., Yuan, Q., Xia, N. S., Sugiyama, M., Nishida, N., Mizokami, M., Chen, C. J., Chen, P. J., & Yang, H. I. (2019). Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection. Clinical Gastroenterology and Hepatology, 17(7), 1413-1415. https://doi.org/10.1016/j.cgh.2018.09.037

@article{df05669020ba4e07b04aa5e15c8233e2,

title = "Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection",

abstract = "For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).1 Predictors of HBeAg seroclearance include lower HBV DNA levels, viral genotype, the precore mutation, and higher serum alanine aminotransferase (ALT) levels.2",

author = "Jessica Liu and Hu, {Hui Han} and Chang, {Chia Ling} and Jen, {Chin Lan} and Lee, {Mei Hsuan} and Lu, {Sheng Nan} and Wang, {Li Yu} and Quan Yuan and Xia, {Ning Shao} and Masaya Sugiyama and Nao Nishida and Masashi Mizokami and Chen, {Chien Jen} and Chen, {Pei Jer} and Yang, {Hwai I.}",

note = "Publisher Copyright: {\textcopyright} 2019 AGA Institute",

year = "2019",

month = jun,

doi = "10.1016/j.cgh.2018.09.037",

language = "English",

volume = "17",

pages = "1413--1415",

journal = "Clinical Gastroenterology and Hepatology",

issn = "1542-3565",

publisher = "W.B. Saunders",

number = "7",

}

Liu, J, Hu, HH, Chang, CL, Jen, CL, Lee, MH, Lu, SN, Wang, LY, Yuan, Q, Xia, NS, Sugiyama, M, Nishida, N, Mizokami, M, Chen, CJ, Chen, PJ & Yang, HI 2019, 'Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection', Clinical Gastroenterology and Hepatology, vol. 17, no. 7, pp. 1413-1415. https://doi.org/10.1016/j.cgh.2018.09.037

Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection. / Liu, Jessica; Hu, Hui Han; Chang, Chia Ling et al.
In: Clinical Gastroenterology and Hepatology, Vol. 17, No. 7, 06.2019, p. 1413-1415.

Research output: Contribution to journal › Short survey › peer-review

TY - JOUR

T1 - Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection

AU - Liu, Jessica

AU - Hu, Hui Han

AU - Chang, Chia Ling

AU - Jen, Chin Lan

AU - Lee, Mei Hsuan

AU - Lu, Sheng Nan

AU - Wang, Li Yu

AU - Yuan, Quan

AU - Xia, Ning Shao

AU - Sugiyama, Masaya

AU - Nishida, Nao

AU - Mizokami, Masashi

AU - Chen, Chien Jen

AU - Chen, Pei Jer

AU - Yang, Hwai I.

PY - 2019/6

Y1 - 2019/6

N2 - For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).1 Predictors of HBeAg seroclearance include lower HBV DNA levels, viral genotype, the precore mutation, and higher serum alanine aminotransferase (ALT) levels.2

AB - For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).1 Predictors of HBeAg seroclearance include lower HBV DNA levels, viral genotype, the precore mutation, and higher serum alanine aminotransferase (ALT) levels.2

UR - http://www.scopus.com/inward/record.url?scp=85060096821&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2018.09.037

DO - 10.1016/j.cgh.2018.09.037

M3 - Short survey

C2 - 30267868

AN - SCOPUS:85060096821

SN - 1542-3565

VL - 17

SP - 1413

EP - 1415

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 7

ER -

Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection

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