TY - JOUR
T1 - Association between Air Quality Index and the risk of rosacea
T2 - A nationwide population-based cohort study
AU - Ma, Sheng Hsiang
AU - Wu, Chun Ying
AU - Li, Meng Chieh
AU - Ho, Hsiu J.
AU - Ao, Chon Kit
AU - Wu, Chen Yi
N1 - Publisher Copyright:
© 2024 The Author(s).
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Background: Air pollution is associated with several inflammatory skin disorders. However, the association between air quality and rosacea remains unclear. Objectives: To investigate the association between the Air Quality Index (AQI) and incidence of rosacea. Methods: In total, 21 709 479 participants without rosacea before 2008 were recruited from the Taiwan National Health Insurance Research Database. The long-term average AQI value for each participant was acquired from the Taiwan Air Quality Monitoring System Network and calculated from 1 January 2008 until the diagnosis of rosacea, withdrawal from the National Health Insurance programme, or 31 December 2018. Results: We observed a significant association between AQI and the incidence of rosacea, with each unit elevation in the AQI increasing the risk of rosacea by 5%. We then categorized participants equally into four groups by quantiles (Q) of AQI values, with mean AQI values of: Q1, 69.0 (SD 6.4); Q2, 79.0 (SD 2.3); Q3, 89.9 (SD 3.6); and Q4, 103.9 (SD 6.8). Compared with the Q1 group, the Q2, Q3 and Q4 cohorts exhibited 1.82-fold, 4.48-fold and 7.22-fold increased risk of rosacea, respectively. Additionally, exposure to particulate matter (PM)2.5 (airborne particulate matter with a diameter ≤ 2.5 μm), sulfur dioxide (SO2) and carbon monoxide increased the risk of rosacea, whereas exposure to PM10 (airborne PM with a diameter ≤ 10 μm) was associated with a lower risk. Conclusions: This study supported a significant dose-response relationship between AQI and the incidence of rosacea.
AB - Background: Air pollution is associated with several inflammatory skin disorders. However, the association between air quality and rosacea remains unclear. Objectives: To investigate the association between the Air Quality Index (AQI) and incidence of rosacea. Methods: In total, 21 709 479 participants without rosacea before 2008 were recruited from the Taiwan National Health Insurance Research Database. The long-term average AQI value for each participant was acquired from the Taiwan Air Quality Monitoring System Network and calculated from 1 January 2008 until the diagnosis of rosacea, withdrawal from the National Health Insurance programme, or 31 December 2018. Results: We observed a significant association between AQI and the incidence of rosacea, with each unit elevation in the AQI increasing the risk of rosacea by 5%. We then categorized participants equally into four groups by quantiles (Q) of AQI values, with mean AQI values of: Q1, 69.0 (SD 6.4); Q2, 79.0 (SD 2.3); Q3, 89.9 (SD 3.6); and Q4, 103.9 (SD 6.8). Compared with the Q1 group, the Q2, Q3 and Q4 cohorts exhibited 1.82-fold, 4.48-fold and 7.22-fold increased risk of rosacea, respectively. Additionally, exposure to particulate matter (PM)2.5 (airborne particulate matter with a diameter ≤ 2.5 μm), sulfur dioxide (SO2) and carbon monoxide increased the risk of rosacea, whereas exposure to PM10 (airborne PM with a diameter ≤ 10 μm) was associated with a lower risk. Conclusions: This study supported a significant dose-response relationship between AQI and the incidence of rosacea.
UR - https://www.scopus.com/pages/publications/85214318518
U2 - 10.1093/ced/llae291
DO - 10.1093/ced/llae291
M3 - Article
C2 - 39067059
AN - SCOPUS:85214318518
SN - 0307-6938
VL - 50
SP - 69
EP - 76
JO - Clinical and Experimental Dermatology
JF - Clinical and Experimental Dermatology
IS - 1
ER -