@inproceedings{65f28910e15a4744a58f7278fabb16b6,
title = "Assessments of urine cofilin-1 in patients hospitalized in the intensive care units with acute kidney injury",
abstract = "The actin depolymerizing factor (ADF)/cofilin protein family has been reported to be associated with ischemia induced renal disorders. Here we examine if cofilin-1 is associated with acute kidney injury (AKI). We exploited a 96-well based fiber-optic biosensor that uses conjugated gold nanoparticles and a sandwich immunoassay to detect the urine cofilin-1 level of AKI patients. The mean urine cofilin-1 level of the AKI patients was two-fold higher than that of healthy adults. The receiver operating characteristic (ROC) curve showed that cofilin-1 is a potential biomarker for discriminating AKI patients from healthy adults for intensive care patients.",
keywords = "acute kidney injury, gold nanoparticle conjugated biosensor, oxidative stress, urine cofilin-1",
author = "Lee, {Yi Jang} and Chao, {Cheng Han} and Chang, {Ying Feng} and Chien Chou",
year = "2013",
doi = "10.1117/12.2001000",
language = "English",
isbn = "9780819493514",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Biophotonics and Immune Responses VIII",
note = "Biophotonics and Immune Responses VIII ; Conference date: 04-02-2013 Through 04-02-2013",
}