Assessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography

Wen Chuan Kuo; Ming Wei Hsiung; Jeou Jong Shyu; Nai Kuan Chou; Po Nien Yang

doi:10.1364/OE.16.008117

Assessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography

Wen Chuan Kuo^*, Ming Wei Hsiung, Jeou Jong Shyu, Nai Kuan Chou, Po Nien Yang

^*Corresponding author for this work

Institute of Biophotonics

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

In this research, we assessed arterial characteristics in human atherosclerosis by determining both scattering and birefringence properties of vessel tissue from polarization-sensitive optical coherence tomography (PS-OCT) images. We demonstrated that optical characteristics including scattering coefficient (μ_s), effective anisotropy factor (g_eff), birefringence coefficient (δn), and fast-axis angle (β) of normal and different kinds of atherosclerotic lesions in human vessels can be quantitatively described. Based on our findings, a quantitative PS-OCT image criterion for plaque characterization was constructed.

Original language	English
Pages (from-to)	8117-8125
Number of pages	9
Journal	Optics Express
Volume	16
Issue number	11
DOIs	https://doi.org/10.1364/OE.16.008117
State	Published - 26 May 2008

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abstract = "In this research, we assessed arterial characteristics in human atherosclerosis by determining both scattering and birefringence properties of vessel tissue from polarization-sensitive optical coherence tomography (PS-OCT) images. We demonstrated that optical characteristics including scattering coefficient (μs), effective anisotropy factor (geff), birefringence coefficient (δn), and fast-axis angle (β) of normal and different kinds of atherosclerotic lesions in human vessels can be quantitatively described. Based on our findings, a quantitative PS-OCT image criterion for plaque characterization was constructed.",

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AU - Kuo, Wen Chuan

AU - Hsiung, Ming Wei

AU - Shyu, Jeou Jong

AU - Chou, Nai Kuan

AU - Yang, Po Nien

PY - 2008/5/26

Y1 - 2008/5/26

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AB - In this research, we assessed arterial characteristics in human atherosclerosis by determining both scattering and birefringence properties of vessel tissue from polarization-sensitive optical coherence tomography (PS-OCT) images. We demonstrated that optical characteristics including scattering coefficient (μs), effective anisotropy factor (geff), birefringence coefficient (δn), and fast-axis angle (β) of normal and different kinds of atherosclerotic lesions in human vessels can be quantitatively described. Based on our findings, a quantitative PS-OCT image criterion for plaque characterization was constructed.

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Assessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography

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