Are tubular cells not only victims but also perpetrators in renal fibrosis

Po Tsang Lee; Kang Ju Chou; Hua Chang Fang

doi:10.1038/ki.2012.120

Are tubular cells not only victims but also perpetrators in renal fibrosis

Po Tsang Lee^*, Kang Ju Chou, Hua Chang Fang

^*Corresponding author for this work

Department of Internal Medicine

Research output: Contribution to journal › Comment/debate

11 Scopus citations

Abstract

Renal fibrosis plays a major role in the progression of renal failure. Determining whether the tubule or the glomerulus is the initiating factor is made difficult by the complexity of disease processes. This Commentary discusses new findings by Grgic et al., who show that acute injury to the renal tubule is sufficient to produce the full spectrum of renal fibrosis.

Original language	English
Pages (from-to)	128-130
Number of pages	3
Journal	Kidney International
Volume	82
Issue number	2
DOIs	https://doi.org/10.1038/ki.2012.120
State	Published - 2 Jul 2012

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10.1038/ki.2012.120

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abstract = "Renal fibrosis plays a major role in the progression of renal failure. Determining whether the tubule or the glomerulus is the initiating factor is made difficult by the complexity of disease processes. This Commentary discusses new findings by Grgic et al., who show that acute injury to the renal tubule is sufficient to produce the full spectrum of renal fibrosis.",

author = "Lee, {Po Tsang} and Chou, {Kang Ju} and Fang, {Hua Chang}",

note = "Funding Information: This work was supported in part by grants from Kaohsiung Veterans General Hospital (VGHKS99-28) and the National Science Council (NSC 100-2314-B-075B-003) to Po-Tsang Lee.",

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AU - Fang, Hua Chang

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N2 - Renal fibrosis plays a major role in the progression of renal failure. Determining whether the tubule or the glomerulus is the initiating factor is made difficult by the complexity of disease processes. This Commentary discusses new findings by Grgic et al., who show that acute injury to the renal tubule is sufficient to produce the full spectrum of renal fibrosis.

AB - Renal fibrosis plays a major role in the progression of renal failure. Determining whether the tubule or the glomerulus is the initiating factor is made difficult by the complexity of disease processes. This Commentary discusses new findings by Grgic et al., who show that acute injury to the renal tubule is sufficient to produce the full spectrum of renal fibrosis.

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Are tubular cells not only victims but also perpetrators in renal fibrosis

Abstract

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