Aqueous Self-Assembly of Hydrophobic Molecules Influenced by the Molecular Geometry

Jia Chen; Linlin Zheng; Xiaohuan Ji; Jin Wen; Chien Lung Wang; Liping Zhu; Bin Sun; Xiaosong Wang; Meifang Zhu

doi:10.1021/acs.jpcb.1c10305

Aqueous Self-Assembly of Hydrophobic Molecules Influenced by the Molecular Geometry

Jia Chen, Linlin Zheng, Xiaohuan Ji, Jin Wen, Chien Lung Wang, Liping Zhu^*, Bin Sun^*, Xiaosong Wang^*, Meifang Zhu

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Water, in addition to acting as a solvent, plays a constructional role in aqueous self-assembly. The hydrophobic molecule of POSS-PDI-POSS (POSS = polyhedral oligomeric silsesquioxanes, PDI = perylene diimide) has a shape anisotropy in which POSS is a ball-like bulky group and PDI is a flat aromatic group. The self-assembly of this molecule in water created assemblies with inner spaces due to the steric effect, which suppressed aromatic interactions of PDI and trapped water for the colloidal stability. By replacing POSS with dodecyl (C₁₂), C₁₂-PDI-C₁₂ aggregated with extended aromatic interaction of PDI and less inner water. The resulting aggregates tended to agglomerate and precipitate. This discovery extended the scope of aqueous self-assembly by using the building blocks without amphiphilicity and created knowledge for biophysics.

Original language	English
Pages (from-to)	1334-1340
Number of pages	7
Journal	Journal of Physical Chemistry B
Volume	126
Issue number	6
DOIs	https://doi.org/10.1021/acs.jpcb.1c10305
State	Published - 17 Feb 2022

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title = "Aqueous Self-Assembly of Hydrophobic Molecules Influenced by the Molecular Geometry",

abstract = "Water, in addition to acting as a solvent, plays a constructional role in aqueous self-assembly. The hydrophobic molecule of POSS-PDI-POSS (POSS = polyhedral oligomeric silsesquioxanes, PDI = perylene diimide) has a shape anisotropy in which POSS is a ball-like bulky group and PDI is a flat aromatic group. The self-assembly of this molecule in water created assemblies with inner spaces due to the steric effect, which suppressed aromatic interactions of PDI and trapped water for the colloidal stability. By replacing POSS with dodecyl (C12), C12-PDI-C12 aggregated with extended aromatic interaction of PDI and less inner water. The resulting aggregates tended to agglomerate and precipitate. This discovery extended the scope of aqueous self-assembly by using the building blocks without amphiphilicity and created knowledge for biophysics.",

author = "Jia Chen and Linlin Zheng and Xiaohuan Ji and Jin Wen and Wang, {Chien Lung} and Liping Zhu and Bin Sun and Xiaosong Wang and Meifang Zhu",

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AU - Chen, Jia

AU - Zheng, Linlin

AU - Ji, Xiaohuan

AU - Wen, Jin

AU - Wang, Chien Lung

AU - Zhu, Liping

AU - Sun, Bin

AU - Wang, Xiaosong

AU - Zhu, Meifang

PY - 2022/2/17

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N2 - Water, in addition to acting as a solvent, plays a constructional role in aqueous self-assembly. The hydrophobic molecule of POSS-PDI-POSS (POSS = polyhedral oligomeric silsesquioxanes, PDI = perylene diimide) has a shape anisotropy in which POSS is a ball-like bulky group and PDI is a flat aromatic group. The self-assembly of this molecule in water created assemblies with inner spaces due to the steric effect, which suppressed aromatic interactions of PDI and trapped water for the colloidal stability. By replacing POSS with dodecyl (C12), C12-PDI-C12 aggregated with extended aromatic interaction of PDI and less inner water. The resulting aggregates tended to agglomerate and precipitate. This discovery extended the scope of aqueous self-assembly by using the building blocks without amphiphilicity and created knowledge for biophysics.

AB - Water, in addition to acting as a solvent, plays a constructional role in aqueous self-assembly. The hydrophobic molecule of POSS-PDI-POSS (POSS = polyhedral oligomeric silsesquioxanes, PDI = perylene diimide) has a shape anisotropy in which POSS is a ball-like bulky group and PDI is a flat aromatic group. The self-assembly of this molecule in water created assemblies with inner spaces due to the steric effect, which suppressed aromatic interactions of PDI and trapped water for the colloidal stability. By replacing POSS with dodecyl (C12), C12-PDI-C12 aggregated with extended aromatic interaction of PDI and less inner water. The resulting aggregates tended to agglomerate and precipitate. This discovery extended the scope of aqueous self-assembly by using the building blocks without amphiphilicity and created knowledge for biophysics.

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JO - Journal of Physical Chemistry B

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ER -

Aqueous Self-Assembly of Hydrophobic Molecules Influenced by the Molecular Geometry

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