AN INTEGRATED MICROFLUIDIC SYSTEM FOR DETECTING CARDIOVASCULAR DISEASE BIOMARKERS

Pei Rong Li, Yu Jen Cheng, Yi Xian Chen, Hsiao Yu Huang, Chih Hung Wang, Tsung Heng Tsai, Chien Nan Kuo, Gwo Bin Lee*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Cardiovascular diseases (CVDs) are lethal diseases with an incidence of 17.9 million patients annually. There are four important biomarkers used in the clinical tests to monitor CVDs. This study presents an integrated, self-driven microfluidic system by using specific-aptamers surface-coated on interdigitated electrodes (IDE) to quantify these biomarkers. Integrated microfluidic modules could achieve sample pre-treatment and liquid manipulation. The IDE biosensors could measure the concentrations of these four biomarkers and then wirelessly transmit them to cellphones. Experimental results showed that this developed system can serve as a promising portable tool for CVDs risk assessment.

Original languageEnglish
Title of host publicationMicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1067-1068
Number of pages2
ISBN (Electronic)9781733419048
StatePublished - 2022
Event26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 - Hybrid, Hangzhou, China
Duration: 23 Oct 202227 Oct 2022

Publication series

NameMicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022
Country/TerritoryChina
CityHybrid, Hangzhou
Period23/10/2227/10/22

Keywords

  • Capillary Microfluidics
  • Cardiovascular Disease
  • Interdigitated Electrodes
  • Plasma Isolation

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