Acute renal failure in severe pancreatitis: A population-based study

Hung Yuan Lin, Jiun I. Lai, Yi Chun Lai, Po Chou Lin, Shih Chieh Chang*, Gau Jun Tang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Introduction. Acute pancreatitis (AP) is a common illness with varied mortality and morbidity. Patients with AP complicated with acute renal failure (ARF) have higher mortality than patients with AP alone. Although ARF has been proposed as a leading mortality cause for AP patients admitted to the ICU, few studies have directly analyzed the relationship between AP and ARF. Methods. We performed a retrospective study using the population-based database from the Taiwan National Health Insurance Research Database (NHIRD). In the period from 1 January 2005 to 31 December 2005, every patient with AP admitted to the ICU was included and assessed for the presence of ARF and mortality risk. Results. In year 2005, there were a total of 221,101 admissions to the ICU. There were 1,734 patients with AP, of which 261 (15.05%) patients also had a diagnosis of ARF. Compared to sepsis and other critical illness, patients with AP had a higher risk of having a diagnosis of ARF, and patients with both diagnoses had a higher mortality rate in the same ICU hospitalization. Conclusion. AP is associated with a higher risk of ARF, and, when both conditions exist, a higher risk of mortality is present.

Original languageEnglish
Pages (from-to)155-159
Number of pages5
JournalUpsala Journal of Medical Sciences
Volume116
Issue number2
DOIs
StatePublished - May 2011

Keywords

  • Acute renal failure
  • intensive care
  • severe acute pancreatitis

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