Absence of infection in breast-fed infants born to hepatitis C virus-infected mothers

Ho Hsiung Lin, Jia Horng Kao, Hong Yuan Hsu, Yen Hsuan Ni, Mei Hwei Chang, Su Cheng Huang, Lih Hwa Hwang, Pei Jer Chen, Ding Shinn Chen

Research output: Contribution to journalArticlepeer-review

183 Scopus citations

Abstract

The role of breast-feeding in perinatal transmission of hepatitis C virus (HCV) was explored in 15 HCV-infected mothers and their infants. The 15 carrier mothers had anti-HCV titers ranging from 1:80 to 1:40,000 and also had HCV-ribonucleic acid with concentrations ranging from 104 to 2.5 × 108 copies/ml. Both anti-HCV antibody and HCV-ribonucleic acid were present in colostral samples in much lower levels, but none of the 11 breast-fed infants had evidence of HCV infection for up to 1 year of age. Thus breast-feeding seems safe for these infants. (J PEDIATR 1995;126:589-91).

Original languageEnglish
Pages (from-to)589-591
Number of pages3
JournalThe Journal of Pediatrics
Volume126
Issue number4
DOIs
StatePublished - Apr 1995

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