A versatile method for generating semiconducting polymer dot nanocomposites

Wei Sun, Sarah Hayden, Yuhui Jin, Yu Rong, Jiangbo Yu, Fangmao Ye, Yang-Hsiang Chan, Max Zeigler, Changfeng Wu, Daniel T. Chiu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


This paper describes a method, based on co-precipitation, for generating small semiconducting polymer dot (Pdot) nanocomposites, which contain either gold or iron oxide nanoparticles within the Pdot matrix. We demonstrate the utility of Pdot-Au nanoparticles (Au-NP-Pdots) in dual-modality imaging in which co-localization of fluorescence from Pdot and scattering from Au was used to identify Au-NP-Pdot probes for downstream single-particle tracking and cellular imaging. We also demonstrate the potential of employing Pdot-FeOx nanoparticles (FeOx-NP-Pdots) for both sample preparation, where cells tagged with FeOx-NP-Pdots were isolated using an external magnet, and cellular imaging and detection, owing to the intense fluorescence from Pdots. The method we present here should be generalizable to the formation of other Pdot nanocomposites for creating the next generation of multi-functional Pdot probes.

Original languageEnglish
Pages (from-to)7246-7249
Number of pages4
Issue number22
StatePublished - 1 Dec 2012


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