A programmable implantable microstimulator soc with wireless telemetry: Application in closed-loop endocardial stimulation for cardiac pacemaker

Shuenn Yuh Lee*, Mario Yucheng Su, Ming Chun Liang, You Yin Chen, Cheng Han Hsieh, Chung Min Yang, Hsin Yi Lai, Jou Wei Lin, Qiang Fang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

A low-power, wireless, and implantable microstimulator system on chip with smart powering management, immediate neural signal acquisition, and wireless rechargeable system is proposed. A system controller with parity checking handles the adjustable stimulus parameters for the stimulated objective. In the current paper, the rat's intra-cardiac electrogram is employed as the stimulated model in the animal study, and it is sensed by a low-voltage and low-power monitoring analog front end. The power management unit, which includes a rectifier, battery charging and detection, and a regulator, is used for the power control of the internal circuits. The stimulation data and required clock are extracted by a phase-locked-loop-based phase shift keying demodulator from an inductive AC signal. The full chip, which consumes 48 $\mu {\rm W}$ only, is fabricated in a TSMC 0.35 $ \mu {\rm m}$ 2P4M standard CMOS process to perform the monitoring and pacing functions with inductively powered communication in the in vivo study.

Original languageEnglish
Article number6101569
Pages (from-to)511-522
Number of pages12
JournalIEEE Transactions on Biomedical Circuits and Systems
Volume5
Issue number6
DOIs
StatePublished - Dec 2011

Keywords

  • Endocardial stimulation
  • Pacemaker
  • Power management
  • Programmable implantable stimulator
  • Wireless telemetry

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