A portable surface plasmon resonance biosensor capable of phase interrogation in a large dynamic range

How Foo Chen, Hsin Yuan Chuang, Chih Hang Chen, Yun Hsiang Chang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

With the development of a point of care (POC) biosensor in mind, a polymer-molding prism with double parabolic surfaces is invented and developed to implement an ultra-compact SPR biosensor with extremely high sensitivity. The polymer molded parabolic prism is cost effective and disposable, thus cross contamination between biological samples can be avoided. A highly sensitive biosensor with a form factor less than 15cm∗15cm∗5cm was received with a tunable excitation angle of light beam for a large dynamic range. A highly sensitive optical phase interrogation was demonstrated. The biosensor is also compatible to a modern microscopy platform.

Original languageEnglish
Title of host publicationBiosensing and Nanomedicine VII
EditorsMassoud H. Agahi, Hooman Mohseni, Manijeh Razeghi
PublisherSPIE
ISBN (Electronic)1628411937, 9781628411935
DOIs
StatePublished - 2014
EventBiosensing and Nanomedicine VII - San Diego, United States
Duration: 17 Aug 2014 → …

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9166
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceBiosensing and Nanomedicine VII
Country/TerritoryUnited States
CitySan Diego
Period17/08/14 → …

Keywords

  • Biological sensing
  • free form optical design
  • microscope compatibility
  • phase interrogation
  • polymer molding
  • sensor
  • Surface plasmon resonance
  • tunable excitation angle

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