A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and Impedance-Boosting Techniques

Yi Jie Lin; Wei Cheng Liu; Yu Chiao Huang; Ying Jie Huang; Yung Hua Yeh; Min Hua Chang; Shu Ping Lin; Ying Chih Liao; Yu Te Liao

doi:10.1109/TBCAS.2023.3287835

A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and Impedance-Boosting Techniques

Yi Jie Lin, Wei Cheng Liu, Yu Chiao Huang, Ying Jie Huang, Yung Hua Yeh, Min Hua Chang, Shu Ping Lin, Ying Chih Liao, Yu Te Liao^*

^*Corresponding author for this work

Department of Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

This article presents a multimodal electrochemical sensing system-on-chip (SoC), including the functions of cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and temperature sensing. CV readout circuitry achieves an adaptive readout current range of 145.5 dB through an automatic range adjustment and resolution scaling technique. EIS has an impedance resolution of 9.2 mΩ Hz at a sweep frequency of 10 kHz and an output current of up to 120 μA. With an impedance boost mechanism, the maximum detectable load impedance is extended to 22.95 kΩ, while the total harmonic distortion is less than 1%. A resistor-based temperature sensor using a swing-boosted relaxation oscillator can achieve a resolution of 31 mK in 0-85 °C. The design is implemented in a 0.18 μm CMOS process. The total power consumption is 1 mW.

Original language	English
Pages (from-to)	857-871
Number of pages	15
Journal	IEEE Transactions on Biomedical Circuits and Systems
Volume	17
Issue number	4
DOIs	https://doi.org/10.1109/TBCAS.2023.3287835
State	Published - 1 Aug 2023

Keywords

CMOS
Electrical Impedance Spectroscopy
Electrochemical
Impedance Boosting
Multimodality
Wide Range

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10.1109/TBCAS.2023.3287835

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Lin, Y. J., Liu, W. C., Huang, Y. C., Huang, Y. J., Yeh, Y. H., Chang, M. H., Lin, S. P., Liao, Y. C., & Liao, Y. T. (2023). A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and Impedance-Boosting Techniques. IEEE Transactions on Biomedical Circuits and Systems, 17(4), 857-871. https://doi.org/10.1109/TBCAS.2023.3287835

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title = "A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and Impedance-Boosting Techniques",

abstract = "This article presents a multimodal electrochemical sensing system-on-chip (SoC), including the functions of cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and temperature sensing. CV readout circuitry achieves an adaptive readout current range of 145.5 dB through an automatic range adjustment and resolution scaling technique. EIS has an impedance resolution of 9.2 mΩ Hz at a sweep frequency of 10 kHz and an output current of up to 120 μA. With an impedance boost mechanism, the maximum detectable load impedance is extended to 22.95 kΩ, while the total harmonic distortion is less than 1%. A resistor-based temperature sensor using a swing-boosted relaxation oscillator can achieve a resolution of 31 mK in 0-85 °C. The design is implemented in a 0.18 μm CMOS process. The total power consumption is 1 mW.",

keywords = "CMOS, Electrical Impedance Spectroscopy, Electrochemical, Impedance Boosting, Multimodality, Wide Range",

author = "Lin, {Yi Jie} and Liu, {Wei Cheng} and Huang, {Yu Chiao} and Huang, {Ying Jie} and Yeh, {Yung Hua} and Chang, {Min Hua} and Lin, {Shu Ping} and Liao, {Ying Chih} and Liao, {Yu Te}",

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doi = "10.1109/TBCAS.2023.3287835",

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AU - Huang, Ying Jie

AU - Yeh, Yung Hua

AU - Chang, Min Hua

AU - Lin, Shu Ping

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AU - Liao, Yu Te

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AB - This article presents a multimodal electrochemical sensing system-on-chip (SoC), including the functions of cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and temperature sensing. CV readout circuitry achieves an adaptive readout current range of 145.5 dB through an automatic range adjustment and resolution scaling technique. EIS has an impedance resolution of 9.2 mΩ Hz at a sweep frequency of 10 kHz and an output current of up to 120 μA. With an impedance boost mechanism, the maximum detectable load impedance is extended to 22.95 kΩ, while the total harmonic distortion is less than 1%. A resistor-based temperature sensor using a swing-boosted relaxation oscillator can achieve a resolution of 31 mK in 0-85 °C. The design is implemented in a 0.18 μm CMOS process. The total power consumption is 1 mW.

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KW - Electrical Impedance Spectroscopy

KW - Electrochemical

KW - Impedance Boosting

KW - Multimodality

KW - Wide Range

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A Multimodality Electrochemical and Impedance Spectroscopy System-on-a-Chip With Temperature Sensing and Impedance-Boosting Techniques

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