TY - GEN
T1 - A Molecularly Imprinted Polymer /Methylene Blue/Anodic Aluminum Oxide (MIP/MB/AAO) Nanocomposite Electrode for the Detection of Ultra-Low Concentration Troponin T in Urine
AU - Chen, Chieh
AU - Cheng, Yu Ting
AU - Tsai, Hsiao En
N1 - Publisher Copyright:
© 2023 IEEJ.
PY - 2023
Y1 - 2023
N2 - In this paper, a molecularly imprinted polymer/methylene blue/anodic aluminum oxide (MIP/MB/AAO) nanocomposite sensing electrode is presented for direct detection of troponin T (cTnT) in urine for the first time. By combining the unique characteristics of the direct redox reaction of the MB in urine and the high surface area of the AAO template, the nanocomposite electrode can exhibit a low limit of detection (LoD) of 13.02 pg/ml and high sensitivity of 8.75 ×10-4 suitable for ultra-low concentration cTnT monitoring. Because the electrode has the advantages of cost-effective, rapid detection, direct and simple measurement, easy storage, etc., we believe it is adequate for the prediction of cardiac events via cTnT monitoring, thereby improving the quality of life of the patients requiring intensive care.
AB - In this paper, a molecularly imprinted polymer/methylene blue/anodic aluminum oxide (MIP/MB/AAO) nanocomposite sensing electrode is presented for direct detection of troponin T (cTnT) in urine for the first time. By combining the unique characteristics of the direct redox reaction of the MB in urine and the high surface area of the AAO template, the nanocomposite electrode can exhibit a low limit of detection (LoD) of 13.02 pg/ml and high sensitivity of 8.75 ×10-4 suitable for ultra-low concentration cTnT monitoring. Because the electrode has the advantages of cost-effective, rapid detection, direct and simple measurement, easy storage, etc., we believe it is adequate for the prediction of cardiac events via cTnT monitoring, thereby improving the quality of life of the patients requiring intensive care.
KW - anodic aluminum oxide
KW - cardiac troponin T
KW - methylene blue
KW - molecularly imprinted polymer
KW - urine
UR - http://www.scopus.com/inward/record.url?scp=85193506106&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85193506106
T3 - 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
SP - 2018
EP - 2021
BT - 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 22nd International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers 2023
Y2 - 25 June 2023 through 29 June 2023
ER -