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A microfluidic chip integrated with molecular imprinting polymers for surface plasmon resonance detection

  • Shih Chiang Huang*
  • , Fan Ching Chien
  • , Jan Sheng Lin
  • , Shean-Jen Chen
  • , Wen Janq Chen
  • , Gwo Bin Lee
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

4 Scopus citations

Abstract

This paper reports a novel microfluidic chip integrated with molecular imprinting polymers (MIP) for surface plasmon resonance (SPR) detection of specific label-free bio-samples. The innovative microfluidic biochip is capable of transporting a specific amount of bio-samples inside multiple microchannels using micropumps/microvalves to sensing regions where multiple MIP films are locally deposited such that highly-sensitive, highly-specific bio-sensing could be achieved. With the help of SPR sensing techniques, the microfluidic biochips have the potential to be widely used for bio-sensing applications. While compared to other sensing techniques, the developed system has several advantages, including labeling-free, high sensitivity, capability of quantitative analysis of nano-scale bio-molecules in real-time fashion.

Original languageEnglish
Title of host publicationTRANSDUCERS '05 - 13th International Conference on Solid-State Sensors and Actuators and Microsystems - Digest of Technical Papers
Pages1776-1779
Number of pages4
DOIs
StatePublished - 9 Nov 2005
Event13th International Conference on Solid-State Sensors and Actuators and Microsystems, TRANSDUCERS '05 - Seoul, Korea, Republic of
Duration: 5 Jun 2005 → 9 Jun 2005

Publication series

NameDigest of Technical Papers - International Conference on Solid State Sensors and Actuators and Microsystems, TRANSDUCERS '05
Volume2

Conference

Conference13th International Conference on Solid-State Sensors and Actuators and Microsystems, TRANSDUCERS '05
Country/TerritoryKorea, Republic of
CitySeoul
Period5/06/05 → 9/06/05

Keywords

  • Microfluidic
  • Micropumps
  • MIP
  • SPR

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