A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor

Sathya Vijayakumar; Lavanya Raja; Srinivasadesikan Venkatesan; Ming Chang Lin; Padmini Vediappen

doi:10.1007/s10895-023-03298-w

A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor

Sathya Vijayakumar, Lavanya Raja, Srinivasadesikan Venkatesan, Ming Chang Lin, Padmini Vediappen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

<?qj left?>Abstract: A simple imine derivative based sensor (IDP) has been synthesized and characterized by ¹ H NMR, ¹³ C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows “TURN-ON” response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10^{− 8} mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples. Graphical Abstract: [Figure not available: see fulltext.].

Original language	English
Journal	Journal of Fluorescence
DOIs	https://doi.org/10.1007/s10895-023-03298-w
State	Accepted/In press - 2023

Keywords

Competitive experiment
Fluorimetry biosensor
LOD
PFOA

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10.1007/s10895-023-03298-w

Cite this

@article{11d6d0004e13413dadfc980e3970daad,

title = "A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor",

abstract = "<?qj left?>Abstract: A simple imine derivative based sensor (IDP) has been synthesized and characterized by 1 H NMR, 13 C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows “TURN-ON” response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10− 8 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples. Graphical Abstract: [Figure not available: see fulltext.].",

keywords = "Competitive experiment, Fluorimetry biosensor, LOD, PFOA",

author = "Sathya Vijayakumar and Lavanya Raja and Srinivasadesikan Venkatesan and Lin, {Ming Chang} and Padmini Vediappen",

note = "Publisher Copyright: {\textcopyright} 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2023",

doi = "10.1007/s10895-023-03298-w",

language = "English",

journal = "Journal of Fluorescence",

issn = "1053-0509",

publisher = "Springer New York",

}

TY - JOUR

T1 - A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor

AU - Vijayakumar, Sathya

AU - Raja, Lavanya

AU - Venkatesan, Srinivasadesikan

AU - Lin, Ming Chang

AU - Vediappen, Padmini

PY - 2023

Y1 - 2023

N2 - <?qj left?>Abstract: A simple imine derivative based sensor (IDP) has been synthesized and characterized by 1 H NMR, 13 C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows “TURN-ON” response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10− 8 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples. Graphical Abstract: [Figure not available: see fulltext.].

AB - <?qj left?>Abstract: A simple imine derivative based sensor (IDP) has been synthesized and characterized by 1 H NMR, 13 C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows “TURN-ON” response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10− 8 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples. Graphical Abstract: [Figure not available: see fulltext.].

KW - Competitive experiment

KW - Fluorimetry biosensor

KW - LOD

KW - PFOA

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U2 - 10.1007/s10895-023-03298-w

DO - 10.1007/s10895-023-03298-w

M3 - Article

AN - SCOPUS:85163372285

SN - 1053-0509

JO - Journal of Fluorescence

JF - Journal of Fluorescence

ER -

A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor

Abstract

Keywords

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