A fully-aqueous red-fluorescent probe for selective optical sensing of Hg2+ and its application in living cells

Murali Krishna Pola; Mandapati V. Ramakrishnam Raju; Chein Ming Lin; Raghunath Putikam; Ming-Chang Lin; Chandra Prakash Epperla; Huan Cheng Chang; San-Yuan Chen; Hong-Cheu Lin

doi:10.1016/j.dyepig.2016.03.028

A fully-aqueous red-fluorescent probe for selective optical sensing of Hg²⁺ and its application in living cells

Murali Krishna Pola, Mandapati V. Ramakrishnam Raju, Chein Ming Lin, Raghunath Putikam, Ming-Chang Lin, Chandra Prakash Epperla, Huan Cheng Chang, San-Yuan Chen, Hong-Cheu Lin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A new red-fluorescent mercury ion sensor material is designed and synthesized, which is composed of a tweezer-shaped hydrophilic probe containing bifurcated soft-base atoms N and S coupled with 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) unit. By virtue of the strong electron-accepting nature of TCF unit (as a push-pull chromophore), this designed sensor material can selectively detect Hg²⁺ over various tested metal ions in a 100% aqueous medium via naked-eye and photoluminescence (PL) observations. Theoretical and time-resolved photoluminescence measurements further confirmed the selectivity and reversibility of the probe towards Hg²⁺ via intramolocular charge transfer mechanism in this sensor material. Moreover, the living cell tests by confocal fluorescence images of this sensor material towards Hg²⁺ were also investigated. Finally, distinguished absorption changes and fluorescence quenching spectral appearances allowed us to present the selective optical indicator of Hg²⁺ via TCF moiety for the first time.

Original language	English
Pages (from-to)	256-265
Number of pages	10
Journal	Dyes and Pigments
Volume	130
DOIs	https://doi.org/10.1016/j.dyepig.2016.03.028
State	Published - 1 Jul 2016

Keywords

Aqueous medium
ICT
Living cell
Push-pull chromophore

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10.1016/j.dyepig.2016.03.028

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title = "A fully-aqueous red-fluorescent probe for selective optical sensing of Hg2+ and its application in living cells",

abstract = "A new red-fluorescent mercury ion sensor material is designed and synthesized, which is composed of a tweezer-shaped hydrophilic probe containing bifurcated soft-base atoms N and S coupled with 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) unit. By virtue of the strong electron-accepting nature of TCF unit (as a push-pull chromophore), this designed sensor material can selectively detect Hg2+ over various tested metal ions in a 100% aqueous medium via naked-eye and photoluminescence (PL) observations. Theoretical and time-resolved photoluminescence measurements further confirmed the selectivity and reversibility of the probe towards Hg2+ via intramolocular charge transfer mechanism in this sensor material. Moreover, the living cell tests by confocal fluorescence images of this sensor material towards Hg2+ were also investigated. Finally, distinguished absorption changes and fluorescence quenching spectral appearances allowed us to present the selective optical indicator of Hg2+ via TCF moiety for the first time.",

keywords = "Aqueous medium, ICT, Living cell, Push-pull chromophore",

author = "Pola, {Murali Krishna} and {Ramakrishnam Raju}, {Mandapati V.} and Lin, {Chein Ming} and Raghunath Putikam and Ming-Chang Lin and Epperla, {Chandra Prakash} and Chang, {Huan Cheng} and San-Yuan Chen and Hong-Cheu Lin",

year = "2016",

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doi = "10.1016/j.dyepig.2016.03.028",

language = "English",

volume = "130",

pages = "256--265",

journal = "Dyes and Pigments",

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T1 - A fully-aqueous red-fluorescent probe for selective optical sensing of Hg2+ and its application in living cells

AU - Pola, Murali Krishna

AU - Ramakrishnam Raju, Mandapati V.

AU - Lin, Chein Ming

AU - Putikam, Raghunath

AU - Lin, Ming-Chang

AU - Epperla, Chandra Prakash

AU - Chang, Huan Cheng

AU - Chen, San-Yuan

AU - Lin, Hong-Cheu

PY - 2016/7/1

Y1 - 2016/7/1

N2 - A new red-fluorescent mercury ion sensor material is designed and synthesized, which is composed of a tweezer-shaped hydrophilic probe containing bifurcated soft-base atoms N and S coupled with 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) unit. By virtue of the strong electron-accepting nature of TCF unit (as a push-pull chromophore), this designed sensor material can selectively detect Hg2+ over various tested metal ions in a 100% aqueous medium via naked-eye and photoluminescence (PL) observations. Theoretical and time-resolved photoluminescence measurements further confirmed the selectivity and reversibility of the probe towards Hg2+ via intramolocular charge transfer mechanism in this sensor material. Moreover, the living cell tests by confocal fluorescence images of this sensor material towards Hg2+ were also investigated. Finally, distinguished absorption changes and fluorescence quenching spectral appearances allowed us to present the selective optical indicator of Hg2+ via TCF moiety for the first time.

AB - A new red-fluorescent mercury ion sensor material is designed and synthesized, which is composed of a tweezer-shaped hydrophilic probe containing bifurcated soft-base atoms N and S coupled with 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) unit. By virtue of the strong electron-accepting nature of TCF unit (as a push-pull chromophore), this designed sensor material can selectively detect Hg2+ over various tested metal ions in a 100% aqueous medium via naked-eye and photoluminescence (PL) observations. Theoretical and time-resolved photoluminescence measurements further confirmed the selectivity and reversibility of the probe towards Hg2+ via intramolocular charge transfer mechanism in this sensor material. Moreover, the living cell tests by confocal fluorescence images of this sensor material towards Hg2+ were also investigated. Finally, distinguished absorption changes and fluorescence quenching spectral appearances allowed us to present the selective optical indicator of Hg2+ via TCF moiety for the first time.

KW - Aqueous medium

KW - ICT

KW - Living cell

KW - Push-pull chromophore

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DO - 10.1016/j.dyepig.2016.03.028

M3 - Article

AN - SCOPUS:84962313682

SN - 0143-7208

VL - 130

SP - 256

EP - 265

JO - Dyes and Pigments

JF - Dyes and Pigments

ER -

A fully-aqueous red-fluorescent probe for selective optical sensing of Hg²⁺ and its application in living cells

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Keywords

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