A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Jhe Cyuan Hu; Ai Fen Wendy Feng; Bo Yao Chang; Chun Hung Lin; Kwok-Kong Mong

doi:10.1039/c7ob00839b

A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Jhe Cyuan Hu, Ai Fen Wendy Feng, Bo Yao Chang, Chun Hung Lin, Kwok-Kong Mong^*

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

Original language	English
Pages (from-to)	5345-5356
Number of pages	12
Journal	Organic and Biomolecular Chemistry
Volume	15
Issue number	25
DOIs	https://doi.org/10.1039/c7ob00839b
State	Published - 2017

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10.1039/c7ob00839b

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title = "A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation",

abstract = "A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.",

author = "Hu, \{Jhe Cyuan\} and Feng, \{Ai Fen Wendy\} and Chang, \{Bo Yao\} and Lin, \{Chun Hung\} and Kwok-Kong Mong",

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AU - Hu, Jhe Cyuan

AU - Feng, Ai Fen Wendy

AU - Chang, Bo Yao

AU - Lin, Chun Hung

AU - Mong, Kwok-Kong

PY - 2017

Y1 - 2017

N2 - A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

AB - A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

UR - https://www.scopus.com/pages/publications/85021663067

U2 - 10.1039/c7ob00839b

DO - 10.1039/c7ob00839b

M3 - Article

C2 - 28617506

AN - SCOPUS:85021663067

SN - 1477-0520

VL - 15

SP - 5345

EP - 5356

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 25

ER -

A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Abstract

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