A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Jhe Cyuan Hu; Ai Fen Wendy Feng; Bo Yao Chang; Chun Hung Lin; Kwok-Kong Mong

doi:10.1039/c7ob00839b

A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Jhe Cyuan Hu, Ai Fen Wendy Feng, Bo Yao Chang, Chun Hung Lin, Kwok-Kong Mong^*

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

Original language	English
Pages (from-to)	5345-5356
Number of pages	12
Journal	Organic and Biomolecular Chemistry
Volume	15
Issue number	25
DOIs	https://doi.org/10.1039/c7ob00839b
State	Published - 2017

Access to Document

10.1039/c7ob00839b

Cite this

@article{98f4343fb2794c069569d2abc77e846b,

title = "A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation",

abstract = "A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.",

author = "Hu, {Jhe Cyuan} and Feng, {Ai Fen Wendy} and Chang, {Bo Yao} and Lin, {Chun Hung} and Kwok-Kong Mong",

note = "Publisher Copyright: {\textcopyright} 2017 The Royal Society of Chemistry.",

year = "2017",

doi = "10.1039/c7ob00839b",

language = "English",

volume = "15",

pages = "5345--5356",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "25",

}

TY - JOUR

T1 - A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

AU - Hu, Jhe Cyuan

AU - Feng, Ai Fen Wendy

AU - Chang, Bo Yao

AU - Lin, Chun Hung

AU - Mong, Kwok-Kong

PY - 2017

Y1 - 2017

N2 - A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

AB - A flexible 1,2-cis α-selective glycosylation strategy for a wide range of glycosyl donors and acceptors has been developed, which is based on an in situ adduct transformation protocol. Based on this strategy, both NFM-derived and iodide covalent adducts can be accessed for glycosylation. Using low temperature NMR spectroscopy, the aforementioned glycosyl adducts were detected.

UR - http://www.scopus.com/inward/record.url?scp=85021663067&partnerID=8YFLogxK

U2 - 10.1039/c7ob00839b

DO - 10.1039/c7ob00839b

M3 - Article

C2 - 28617506

AN - SCOPUS:85021663067

SN - 1477-0520

VL - 15

SP - 5345

EP - 5356

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 25

ER -

A flexible 1,2-cis α-glycosylation strategy based on in situ adduct transformation

Abstract

Access to Document

Other files and links

Fingerprint

Cite this