A case of bilateral otomycosis associated with Aspergillus flavus and A. terreus in Taiwan

R. Kirschner; P. L. Sun; S. L. Huang; C. L. Chen; C. P. Yang

doi:10.1016/j.mycmed.2017.04.010

A case of bilateral otomycosis associated with Aspergillus flavus and A. terreus in Taiwan

R. Kirschner^*, P. L. Sun, S. L. Huang, C. L. Chen, C. P. Yang

^*Corresponding author for this work

Institute of Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Otitis externa caused by fungi (otomycosis) occurs more commonly in tropical areas with high moisture than in temperate regions. Bilateral otomycosis is, however, rarely reported. In a case of bilateral otitis externa in a 56-year-old male patient in Taiwan, direct microscopic examination of the cerumen as well as isolation of strains indicated the presence of two Aspergillus species being different in each of both ears. The species were identified by DNA sequence comparisons and additional morphological confirmation of diagnostic characteristics as Aspergillus flavus and Aspergillus terreus. The rarely reported occurrence of two Aspergillus species in otitis of the same patient deserves attention in other cases of otomycosis, particularly with respect to potentially different resistances of different species against antifungals. Treatment with nystatin/neomycin was not successful, but with clotrimazole was effective.

Original language	English
Pages (from-to)	412-416
Number of pages	5
Journal	Journal de Mycologie Medicale
Volume	27
Issue number	3
DOIs	https://doi.org/10.1016/j.mycmed.2017.04.010
State	Published - Sep 2017

Keywords

Beta-tubulin gene
Eurotiales
Hyphomycetes
Internal transcribed spacer (ITS)
Molds

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.mycmed.2017.04.010

Cite this

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title = "A case of bilateral otomycosis associated with Aspergillus flavus and A. terreus in Taiwan",

abstract = "Otitis externa caused by fungi (otomycosis) occurs more commonly in tropical areas with high moisture than in temperate regions. Bilateral otomycosis is, however, rarely reported. In a case of bilateral otitis externa in a 56-year-old male patient in Taiwan, direct microscopic examination of the cerumen as well as isolation of strains indicated the presence of two Aspergillus species being different in each of both ears. The species were identified by DNA sequence comparisons and additional morphological confirmation of diagnostic characteristics as Aspergillus flavus and Aspergillus terreus. The rarely reported occurrence of two Aspergillus species in otitis of the same patient deserves attention in other cases of otomycosis, particularly with respect to potentially different resistances of different species against antifungals. Treatment with nystatin/neomycin was not successful, but with clotrimazole was effective.",

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AU - Yang, C. P.

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