Capacitive sensor array (CSA) plays an important role in life science applications, such as cell monitoring, DNA detection, or drug screening. This brief presents a 480×960 time-sharing TDC (ts-TDC) architecture of global shutter CSA. It provides an opportunity to merge interfacing, read-out and sampling circuits in pixel and dynamically adjust the electrode size according to the characteristic of biosample. Each pixel size is within 2.25× 2.25μ m2. The sensitivity of the proposed CSA is 6.896 codes/fF, and 43 fps can be adopted for real-time monitoring. Experiment results show that noise canceling significantly improves the sensing performance. Moreover, sensitivity can be optimized by given fusion-pixel pattern, making our proposal very flexible and suitable for cell biology applications and personalized medicine.
|Number of pages||5|
|Journal||IEEE Transactions on Circuits and Systems I: Regular Papers|
|State||Published - 1 May 2023|
- capacitance sensor array
- CMOS lab-on-chip
- fusion pixels
- high throughput