Abstract
Capacitive sensor array (CSA) plays an important role in life science applications, such as cell monitoring, DNA detection, or drug screening. This brief presents a 480×960 time-sharing TDC (ts-TDC) architecture of global shutter CSA. It provides an opportunity to merge interfacing, read-out and sampling circuits in pixel and dynamically adjust the electrode size according to the characteristic of biosample. Each pixel size is within 2.25× 2.25μ m2. The sensitivity of the proposed CSA is 6.896 codes/fF, and 43 fps can be adopted for real-time monitoring. Experiment results show that noise canceling significantly improves the sensing performance. Moreover, sensitivity can be optimized by given fusion-pixel pattern, making our proposal very flexible and suitable for cell biology applications and personalized medicine.
Original language | English |
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Pages (from-to) | 1734-1738 |
Number of pages | 5 |
Journal | IEEE Transactions on Circuits and Systems I: Regular Papers |
Volume | 70 |
Issue number | 5 |
DOIs | |
State | Published - 1 May 2023 |
Keywords
- CMOS lab-on-chip
- capacitance sensor array
- fusion pixels
- high throughput
- ts-TDC