2020 Taiwan consensus statement on the management of hepatitis C: Part (II) special populations

Ming Lung Yu*, Pei Jer Chen, Chia Yen Dai, Tsung Hui Hu, Chung Feng Huang, Yi Hsiang Huang, Chao Hung Hung, Chun Yen Lin, Chen Hua Liu, Chun Jen Liu, Cheng Yuan Peng, Han Chieh Lin, Jia Horng Kao, Wan Long Chuang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Hepatitis C virus (HCV) infection is a silent killer that leads to rapid progression of liver cirrhosis and hepatocellular carcinoma (HCC). High prevalence of HCV infection has been reported in Taiwan, especially in high-risk populations including people who inject drugs (PWID) and patients requiring dialysis. Besides, certain populations merit special considerations due to suboptimal outcome, potential drug–drug interaction, or possible side effect. Therefore, in the second part of this 2-part consensus, the Taiwan Association for the Study of the Liver (TASL) proposes the treatment recommendations for the special population in order to serve as guidance to optimizing the outcome in the direct-acting antiviral (DAA) era. Special populations include patients with acute or recent HCV infection, previous DAA failure, chronic kidney disease, decompensated cirrhosis, HCC, liver and other solid organ transplantations, receiving an HCV viremic organ, hepatitis B virus (HBV) and HCV dual infection, HCV and human immunodeficiency virus (HIV) coinfection, active tuberculosis infection, PWID, bleeding disorders and hemoglobinopathies, children and adolescents, and pregnancy. Moreover, future perspectives regarding the management of hepatitis C are also discussed and summarized in this consensus statement.

Original languageEnglish
Pages (from-to)1135-1157
Number of pages23
JournalJournal of the Formosan Medical Association
Volume119
Issue number7
DOIs
StatePublished - Jul 2020

Keywords

  • Consensus
  • DAA
  • HCV
  • Hepatitis C
  • Taiwan
  • TASL

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