Personal profile
Research Interests
- Systems biology - Apply DNA microarray, mass spectrometry, 2-hybrid expression system, and bioinformatics technologies to (i) characterize the biomodules essential for cell survival upon environmental perturbations in Halobacterium sp. NRC-1 and Haloarcula marismortui and (ii) identify the new functions of more than 50% of all the predicted genes in these microorganisms.
- Biomarker discovery - Identify cancer diagnostic markers and therapeutic targets using bioinformatics and mass spectrometry tools.
- Technology development - EST database mining, mass spectrometry, and mass spectrometry data analysis system.
Education/Academic qualification
PhD, Microbiology, University of Massachusetts
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Collaborations and top research areas from the last five years
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A genetic basis of mitochondrial DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma
Chang, C. W., Chen, Y. S., Huang, C. H., Lin, C. H., Ng, W. V., Chu, L. J., Trépo, E., Zucman-Rossi, J., Siao, K., Maher, J. J., Chiew, M. Y., Chou, C. H., Huang, H. D., Teo, W. H., Lee, I. S., Lo, J. F. & Wang, X. W., 1 Jan 2025, In: Hepatology. 81, 1, p. 60-76 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Characterization of young infants with fecal carriage of multidrug-resistant Escherichia coli in Southern Taiwan
Lin, F. C., Ng, W. V., Wang, H. P., Hung, C. H., Chang, J. T., Yang, C. C., Liu, P. Y. & Cheng, M. F., Mar 2024, In: Pediatrics and Neonatology. 65, 2, p. 138-144 7 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Decoding the differentiation of mesenchymal stem cells into mesangial cells at the transcriptomic level
Wong, C. Y., Chang, Y. M., Tsai, Y. S., Ng, W. V., Cheong, S. K., Chang, T. Y., Chung, I. F. & Lim, Y. M., 7 Jul 2020, In: BMC genomics. 21, 1, 467.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
N-acetylgalactosamine-6-sulfatase (GALNS), Similar to Glycodelin, Is a Potential General Biomarker for Multiple Malignancies
Ho, M. L., Kuo, W. K., Chu, L. J., Yeh, I. H., Fan, C. W., Chang, H. I., Yuan, C. L., Chou, T. Y., Chen, H. Y., Yang, S. W., Chang, L. C., Luo, M., Wu, T. H., Chang, Y. F. I., Yu, C. J., Hua, C. C. & Ng, W. V., 2019, In: Anticancer Research. 39, 11, p. 6317-6324 8 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
A transcriptome study of progeroid neurocutaneous syndrome reveals postn as a new element in proline metabolic disorder
Huang, Y. W., Chiang, M. F., Ho, C. S., Hung, P. L., Hsu, M. H., Lee, T. H., Chu, L. J., Liu, H., Tang, P., Ng, W. V. & Lin, D. S., 2018, In: Aging and Disease. 9, 6, p. 1043-1057 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations