Projects per year
Personal profile
Research Interests
Molecular Simulation, Statistical Mechanics, Protein Dynamics, Drug Discovery
Experience
2004/7~2006/8 Postdoctoral Researcher, Department of Chemistry, University of Utah
2006/9~2013/7 Assistant Professor, Department of Chemical and Biomolecular Engineering, University of California, Berkeley
2013/8~ present Professor, Institute of Bioinformatics and Systems Biology, National Chiao Tung University
Education/Academic qualification
PhD, Chemical Engineering, Massachusetts Institute of Technology
External positions
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利用分子模擬和結構機械統計學習分析三端修復外切核酸酶1所具特有活性之分子機制(3/3)
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
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利用分子模擬和結構機械統計學習分析三端修復外切核酸酶1所具特有活性之分子機制(2/3)
1/08/21 → 31/07/22
Project: Government Ministry › Other Government Ministry Institute
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利用分子模擬和結構機械統計學習分析三端修復外切核酸酶1所具特有活性之分子機制(1/3)
1/08/20 → 31/07/21
Project: Government Ministry › Other Government Ministry Institute
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建立多層級模擬計算方法以解譯蛋白質動態與功能(3/3)
1/08/19 → 31/07/20
Project: Government Ministry › Other Government Ministry Institute
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建立多層級模擬計算方法以解譯蛋白質動態與功能(2/3)
1/08/18 → 31/07/19
Project: Government Ministry › Other Government Ministry Institute
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Edge weights in a protein elastic network reorganize collective motions and render long-range sensitivity responses
Yu, C. C., Raj, N. & Chu, J. W., 28 Jun 2022, In: Journal of Chemical Physics. 156, 24, 245105.Research output: Contribution to journal › Article › peer-review
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Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model
Chen, Y. T., Chang, Y. H., Pathak, N., Tzou, S. C., Luo, Y. C., Hsu, Y. C., Li, T. N., Lee, J. Y., Chen, Y. C., Huang, Y. W., Yang, H. J., Hsu, N. Y., Tsai, H. P., Chang, T. Y., Hsu, S. C., Liu, P. C., Chin, Y. F., Lin, W. C., Yang, C. M., Wu, H. L., & 12 others , 21 Dec 2022, In: Frontiers in Immunology. 13, 1080897.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure-mechanics statistical learning uncovers mechanical relay in proteins
Raj, N., Click, T. H., Yang, H. & Chu, J. W., 19 Jan 2022, In: Chemical Science. 13, 13, p. 3688-3696 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Liu, T. C., Lin, C. T., Chang, K. C., Guo, K. W., Wang, S., Chu, J-W. & Hsiao, Y-Y., 27 Jan 2021, In: Nature Communications. 12, 1, p. 1-12 12 p., 601.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Mechanical couplings of protein backbone and side chains exhibit scale-free network properties and specific hotspots for function
Raj, N., Click, T., Yang, H. & Chu, J-W., Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 5309-5320 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations