Research output per year
Research output per year
Personal profile
Research Interests
1. Stem cell differentiation and cancer metastasis: We focus on the topic of the mechanosensitivity of integrin-based focal adhesions, which allow cells to sense and translate biochemical and physical cues from their environment (extracellular matrix components, stiffness or organization) into cellular biological signals that control cell behavior, differentiation, and death. My group focus on investigating how the signals of integrin-based focal adhesions regulate stem cell fate, myogenesis and cancer metastasis.
2. Development of wound healing materials: We have developed a patented method to purify fibronectin. Using the purified fibronectin, my group keep developing the medical materials for wound healing.
Education/Academic qualification
PhD, Molecular Medicine, National Taiwan University
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Collaborations and top research areas from the last five years
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High-viscosity driven modulation of biomechanical properties of human mesenchymal stem cells promotes osteogenic lineage
Chen, Y. Q., Wu, M. C., Wei, M. T., Kuo, J. C., Yu, H. W. & Chiou, A., Jun 2024, In: Materials Today Bio. 26, 101058.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity
Chiang, W. Y., Yu, H. W., Wu, M. C., Huang, Y. M., Chen, Y. Q., Lin, J. W., Liu, Y. W., You, L. R., Chiou, A. & Kuo, J. C., Jul 2024, In: Biomaterials. 308, 122551.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sarcopenia-related changes in serum GLP-1 level affect myogenic differentiation
Huang, H. H., Wang, Y. J., Jiang, H. Y., Yu, H. W., Chen, Y. Q., Chiou, A. & Kuo, J. C., 2024, (Accepted/In press) In: Journal of Cachexia, Sarcopenia and Muscle.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of vessel mimicking microfluidic device for studying mechano-response of endothelial cells
Chu, P. Y., Hsieh, H. Y., Chung, P. S., Wang, P. W., Wu, M. C., Chen, Y. Q., Kuo, J. C. & Fan, Y. J., 16 Jun 2023, In: iScience. 26, 6, 106927.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Early committed polarization of intracellular tension in response to cell shape determines the osteogenic differentiation of mesenchymal stromal cells
Wu, M. C., Yu, H. W., Chen, Y. Q., Ou, M. H., Serrano, R., Huang, G. L., Wang, Y. K., Lin, K. H., Fan, Y. J., Wu, C. C., del Álamo, J. C., Chiou, A., Chien, S. & Kuo, J. C., Jun 2023, In: Acta Biomaterialia. 163, p. 287-301 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations