Personal profile
Research Interests
Cellular and molecular toxicology, Effects of chemicals and drugs on receptors and enzymes of plasma membranes, Roles of calcium in chemically induced cytotoxicity
Education/Academic qualification
PhD, Chemistry and Biochemistry, University of California, San Diego
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Collaborations and top research areas from the last five years
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Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17
Chan, Y. J., Hsiao, G., Wan, W. N., Yang, T. M., Tsai, C. H., Kang, J. J., Lee, Y. C., Fang, T. C., Cheng, Y. W. & Li, C. H., Dec 2023, In: Fluids and Barriers of the CNS. 20, 1, 31.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Safety Evaluation and Anti-Inflammatory Efficacy of Lacticaseibacillus paracasei PS23
Li, C. H., Chen, T. Y., Wu, C. C., Cheng, S. H., Chang, M. Y., Cheng, W. H., Chiu, S. H., Chen, C. C., Tsai, Y. C., Yang, D. J., Kang, J. J. & Liao, P. L., Jan 2023, In: International Journal Of Molecular Sciences. 24, 1, 724.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing
Pathak, N., Chen, Y. T., Hsu, Y. C., Hsu, N. Y., Kuo, C. J., Tsai, H. P., Kang, J.-J., Huang, C. H., Chang, S. Y., Chang, Y. H., Liang, P. H. & Yang, J.-M., 26 Jan 2021, In: ACS Nano. 15, 1, p. 857-872 16 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Aryl hydrocarbon receptor deficiency enhanced airway inflammation and remodeling in a murine chronic asthma model
Chang, Y. D., Li, C. H., Tsai, C. H., Cheng, Y. W., Kang, J. J. & Lee, C. C., 1 Nov 2020, In: FASEB Journal. 34, 11, p. 15300-15313 14 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions
Tsai, C. H., Li, C. H., Liao, P. L., Chang, Y. W., Cheng, Y. W. & Kang, J. J., Feb 2020, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 2, 118564.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations