Projects per year
Personal profile
Research Interests
Natural product chemistry, Enzyme chemistry, Structural biology
Experience
2011/09~2015/01 Postdoctoral Fellow, Genomics Research Center, Academia Sinica
2015/01~2018/03 Postdoctoral research associate, Department of Chemistry, The Scripps Research Institute
2018/04~2018/07 Researcher, Department of Bio-based Chemicals and Biocatalyst, Industrial Technology Research Institute
2018/8~ present Assistant Professor, Department of Biological Science and Technology, National Chiao Tung University
Education/Academic qualification
PhD, Biological Science and Technology, National Yang Ming Chiao Tung University
External positions
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
1/08/23 → 31/07/24
Project: Government Ministry › Other Government Ministry Institute
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
1/08/21 → 31/07/22
Project: Government Ministry › Other Government Ministry Institute
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解析結核放線菌素之生合成途徑並利用改良酵素與化學修飾開發新一代抗TB、MRSA及VRE之抗生素
1/12/20 → 31/07/21
Project: Government Ministry › Other Government Ministry Institute
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解析結核放線菌素之生合成途徑並利用改良酵素與化學修飾開發新一代抗TB、MRSA及VRE之抗生素
1/12/19 → 31/07/20
Project: Government Ministry › Other Government Ministry Institute
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Biomimetic Total Synthesis of the Spiroindimicin Family of Natural Products
Zheng, X., Li, Y., Guan, M., Wang, L., Wei, S., Li, Y. C., Chang, C. Y. & Xu, Z., 2022, (Accepted/In press) In: Angewandte Chemie - International Edition.Research output: Contribution to journal › Article › peer-review
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Characterization and Structural Determination of CmnG-A, the Adenylation Domain That Activates the Nonproteinogenic Amino Acid Capreomycidine in Capreomycin Biosynthesis
Chen, I. H., Cheng, T., Wang, Y. L., Huang, S. J., Hsiao, Y. H., Lai, Y. T., Toh, S. I., Chu, J., Rudolf, J. D. & Chang, C. Y., 16 Dec 2022, In: ChemBioChem. 23, 24, e202200563.Research output: Contribution to journal › Article › peer-review
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Crystal structure of the α-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer
Hsiao, Y. H., Huang, S. J., Lin, E. C., Hsiao, P. Y., Toh, S. I., Chen, I. H., Xu, Z., Lin, Y. P., Liu, H. J. & Chang, C. Y., 13 Sep 2022, In: Frontiers in Chemistry. 10, 1001311.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin
Pan, Y. C., Wang, Y. L., Toh, S. I., Hsu, N. S., Lin, K. H., Xu, Z., Huang, S. C., Wu, T. K., Li, T. L. & Chang, C. Y., 21 Jan 2022, In: ACS Chemical Biology. 17, 1, p. 138-146 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Electroluminescence and photocatalytic hydrogen evolution of S,N co-doped graphene oxide quantum dots
Cheng, T. Y., Chou, F. P., Huang, S. C., Chang, C. Y. & Wu, T. K., 21 Feb 2022, In: Journal of Materials Chemistry A. 10, 7, p. 3650-3658 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations
Prizes
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Academic Publications Award, Ministry of Science and Technology
Chang, Chin-Yuan (Recipient), 2015
Prize: Honorary award