Projects per year
Personal profile
Research Interests
Natural product chemistry, Enzyme chemistry, Structural biology
Experience
2011/09~2015/01 Postdoctoral Fellow, Genomics Research Center, Academia Sinica
2015/01~2018/03 Postdoctoral research associate, Department of Chemistry, The Scripps Research Institute
2018/04~2018/07 Researcher, Department of Bio-based Chemicals and Biocatalyst, Industrial Technology Research Institute
2018/8~ present Assistant Professor, Department of Biological Science and Technology, National Chiao Tung University
Education/Academic qualification
PhD, Biological Science and Technology, National Yang Ming Chiao Tung University
External positions
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Collaborations and top research areas from the last five years
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Projects
- 6 Finished
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
Chang, C.-Y. (PI)
1/08/23 → 31/07/24
Project: Government Ministry › Other Government Ministry Institute
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
Chang, C.-Y. (PI)
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
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Youssoufenes的生物合成研究與化學修飾，發展新型抗生素對抗多重抗藥性菌株
Chang, C.-Y. (PI)
1/08/21 → 31/07/22
Project: Government Ministry › Other Government Ministry Institute
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解析結核放線菌素之生合成途徑並利用改良酵素與化學修飾開發新一代抗TB、MRSA及VRE之抗生素
Chang, C.-Y. (PI)
1/12/20 → 31/07/21
Project: Government Ministry › Other Government Ministry Institute
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解析結核放線菌素之生合成途徑並利用改良酵素與化學修飾開發新一代抗TB、MRSA及VRE之抗生素
Chang, C.-Y. (PI)
1/12/19 → 31/07/20
Project: Government Ministry › Other Government Ministry Institute
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pH-Responsive Polyethylene Glycol Engagers for Enhanced Brain Delivery of PEGylated Nanomedicine to Treat Glioblastoma
Meng, J. L., Dong, Z. X., Chen, Y. R., Lin, M. H., Liu, Y. C., Roffler, S. R., Lin, W. W., Chang, C. Y., Tzou, S. C., Cheng, T. L., Huang, H. C., Li, Z. Q., Lin, Y. C. & Su, Y. C., 14 Jan 2025, In: ACS Nano. 19, 1, p. 307-321 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
“Cofactors” for Natural Products
Chiou, S. L., Chang, C. Y. & Chu, J., 2025, (Accepted/In press) In: ChemMedChem.Research output: Contribution to journal › Article › peer-review
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Integrating molecular dynamics simulation with small- and wide-angle X-ray scattering to unravel the flexibility, antigen-blocking, and protease-restoring functions in a hindrance-based pro-antibody
Liao, J. M., Hong, S. T., Wang, Y. T., Cheng, Y. A., Ho, K. W., Toh, S. I., Shih, O., Jeng, U. S., Lyu, P. C., Hu, I. C., Huang, M. Y., Chang, C. Y. & Cheng, T. L., Sep 2024, In: Protein Science. 33, 9, e5124.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Structure Prediction and Protein Engineering Yield New Insights into Microcin J25 Precursor Recognition
Tan, H. N., Liu, W. Q., Ho, J., Chen, Y. J., Shieh, F. J., Liao, H. T., Wang, S. P., Hegemann, J. D., Chang, C. Y. & Chu, J., 20 Sep 2024, In: ACS Chemical Biology. 19, 9, p. 1982-1990 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Crystal structure of CmnB involved in the biosynthesis of the nonproteinogenic amino acid l-2,3-diaminopropionic acid
Toh, S. I., Lo, C. L. & Chang, C. Y., 5 Jul 2023, In: Acta Crystallographica Section F:Structural Biology Communications. 79, p. 193-199 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Prizes
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Academic Publications Award, Ministry of Science and Technology
Chang, C.-Y. (Recipient), 2015
Prize: Honorary award