Projects per year
Personal profile
Research Interests
Structural bioinformatics, Computer-aided drug design, Machine learning, Systems biology
Education/Academic qualification
PhD, Bioinformatics, National Yang Ming Chiao Tung University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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治療類鴉片藥物使用疾患之潛在標靶:聚焦於PRKAR1B
Lu, C.-H. (PI)
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
Research output
- 26 Article
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Discovery of Novel Spike Inhibitors against SARS-CoV-2 Infection
Tai, L. T., Yeh, C. Y., Chang, Y. J., Liu, J. F., Hsu, K. C., Cheng, J. C. & Lu, C. H., Jun 2024, In: International Journal Of Molecular Sciences. 25, 11, 6105.Research output: Contribution to journal › Article › peer-review
Open Access -
Glycyrrhizic acid conjugates with amino acid methyl esters target the main protease, exhibiting antiviral activity against wild-type and nirmatrelvir-resistant SARS-CoV-2 variants
Le, U. N. P., Chang, Y. J., Lu, C. H., Chen, Y., Su, W. C., Chao, S. T., Baltina, L. A., Petrova, S. F., Li, S. R., Hung, M. C., Lai, M. M. C., Baltina, L. A. & Lin, C. W., Jul 2024, In: Antiviral Research. 227, 105920.Research output: Contribution to journal › Article › peer-review
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Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy
Huang, Y. K., Cheng, W. C., Kuo, T. T., Yang, J. C., Wu, Y. C., Wu, H. H., Lo, C. C., Hsieh, C. Y., Wong, S. C., Lu, C. H., Wu, W. L., Liu, S. J., Li, Y. C., Lin, C. C., Shen, C. N., Hung, M. C., Lin, J. T., Yeh, C. C. & Sher, Y. P., Mar 2024, In: Nature Cancer. 5, 3, p. 400-419 20 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Inhibition of dengue viruses by N-methylcytisine thio derivatives through targeting viral envelope protein and NS2B-NS3 protease
Lin, C. S., Lu, C. H., Lin, T. H., Kiu, Y. T., Kan, J. Y., Chang, Y. J., Hung, P. Y., Koval'skaya, A. V., Tsypyshev, D. O., Tsypysheva, I. P. & Lin, C. W., 1 Feb 2024, In: Bioorganic and Medicinal Chemistry Letters. 99, 129623.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Combining virtual screening with cis-/trans-cleavage enzymatic assays effectively reveals broad-spectrum inhibitors that target the main proteases of SARS-CoV-2 and MERS-CoV
Chang, Y. J., Le, U. N. P., Liu, J. J., Li, S. R., Chao, S. T., Lai, H. C., Lin, Y. F., Hsu, K. C., Lu, C. H. & Lin, C. W., Aug 2023, In: Antiviral Research. 216, 105653.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations