Projects per year
Organization profile
organization profile
The NCTU Bioinformatics and Systems Biology Institute is the first Institute of Bioinformatics and is ranked among the best in Taiwan, as evidenced by the excellence of the faculty and students as well as the quality of interdisciplinary educational programs. The Major is designed for highly motivated students interested in interdisciplinary activities in life sciences, computer science, statistics, systems biology, and computational biology. Leading the Institute's research and teaching activities are 10 professors and 5 core facilities (e.g. over 300-cpu PC clusters and 40 MAC computers). The Institute has over 28 and 40 graduate students pursuing master and doctorate degrees, respectively.
The NCTU Institute of Bioinformatics and Systems Biology carries out research in structural bioinformatics, systems biology (e.g. gene networks and metabolic pathways), drug discovery, biological databases and algorithms, molecular evolution, computational chemistry, and functional genomics. Supporting by National Science Council and Ministry of Education, the Institute has installed the sole Structural Bioinformatics and Computer-aided Drug Design Core Facilities. On average, each faculty publishes 5 papers/year and the sum of impact factor is over 20/year; and the grant is over 3,000,000/year. These Principle Investigators have produced renowned computational packages and databases: GEMDOCK, for drug design; 3D-BLAST, for a super fast structure database search; miRNAMap, genomic maps of microRNAs in mammalian genomes; and CELLO, for sub-cellular localization prediction.
The Molecular Bioinformatics Center (MBC) was established in 2006 as a national resource for bioinformatics and computational systems biology in Taiwan. MBC performs research in computational biology, develops software tools and novel algorithms for analyzing biological data and creates public databases. The research areas cover protein structure prediction and classification, computational drug docking, protein thermostability prediction, data mining, RNA secondary structure prediction and large-scale genomic sequence alignment.
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Network
Profiles
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從患者個體至單細胞之癌症聚焦網路應用於開發個人化生物標記及癌症治療(4/5)
1/09/22 → 31/08/23
Project: Government Ministry › Other Government Ministry Institute
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透過整合生物資訊、基礎實驗及臨床轉譯醫學研究以全方位探討非酒精性脂肪肝炎之新穎治療標靶及致病機制-藉由智慧計算模型探討非酒精性脂肪肝炎的致病機制、生物標誌及治療藥物(2/3)
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
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以多體學資料系統性探討腫瘤微環境及腫瘤演化與腫瘤中關鍵變異之關聯性並評估其臨床應用潛力
1/08/22 → 31/07/23
Project: Government Ministry › Other Government Ministry Institute
Research output
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Gut microbiota composition can reflect immune responses of latent tuberculosis infection in patients with poorly controlled diabetes
Huang, H. L., Luo, Y. C., Lu, P. L., Huang, C. H., Lin, K. D., Lee, M. R., Cheng, M. H., Yeh, Y. T., Kao, C. Y., Wang, J. Y., Yang, J. M. & Chong, I. W., Dec 2023, In: Respiratory Research. 24, 1, 11.Research output: Contribution to journal › Article › peer-review
Open Access -
Amelioration of Maternal Immune Activation-Induced Autism Relevant Behaviors by Gut Commensal Parabacteroides goldsteinii
Lin, T. L., Lu, C. C., Chen, T. W., Huang, C. W., Lu, J. J., Lai, W. F., Wu, T. S., Lai, C. H., Lai, H. C. & Chen, Y. L., Nov 2022, In: International Journal Of Molecular Sciences. 23, 21, 13070.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel graph convolutional neural network for predicting interaction sites on protein kinase inhibitors in phosphorylation
Wang, F., Chen, Y. T., Yang, J. M. & Akutsu, T., Dec 2022, In: Scientific reports. 12, 1, 229.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Prizes
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13th Macronix Golden Silicon Awards Semiconductor Design and Application Competition, Second Runner-up in Application Category
Ko, Li-Wei (Recipient), 2013
Prize: Honorary award
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15th Macronix Golden Silicon Awards Semiconductor Design and Application Competition, Third Runner-up in Application Category
Ko, Li-Wei (Recipient), 2015
Prize: Honorary award
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Academic achievement award in the Institute of Bioinformatics and Systems Biology, National Chiao Tung University
Lin, Chun-Yu (Recipient), 2009
Prize: Honorary award
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IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (Event)
Li-Wei Ko (Member of editorial board)
1 Jan 2018 → 31 Dec 2018Activity: Publication peer-review and editorial work › Editorial work
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Scientific Reports (Event)
Jinn-Moon Yang (Member of editorial board)
1 Jan 2017 → 22 Dec 2018Activity: Publication peer-review and editorial work › Editorial work
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PLoS One (Event)
Jinn-Moon Yang (Member of editorial board)
1 Jan 2017 → 31 Dec 2018Activity: Publication peer-review and editorial work › Editorial work