Research output per year
Research output per year
Research output
- 1 - 50 out of 500 results
Search results
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2024
Aldo-keto reductase family member C3 (AKR1C3) promotes hepatocellular carcinoma cell growth by producing prostaglandin F2α
Jeng, K. S., Cheng, P. Y., Lin, Y. H., Liu, P. C., Tseng, P.-H., Wang, Y. C., Chang, C. F. & Leu, C. M., 2024, In: Oncology Research. 32, 1, p. 163-174 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Analysis of Human Endogenous mRNA Deadenylation Complexes by High-Resolution Gel Electrophoresis
Chang, C. T., 2024, Methods in Molecular Biology. Humana Press Inc., p. 47-54 8 p. (Methods in Molecular Biology; vol. 2723).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Correction: PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target (Cell Death & Disease, (2023), 14, 10, (671), 10.1038/s41419-023-06201-4)
Singh, S., Yeat, N. Y., Wang, Y. T., Lin, S. Y., Kuo, I. Y., Wu, K. P., Wang, W. J., Wang, W. C., Su, W. C., Wang, Y. C. & Chen, R. H., Jul 2024, In: Cell Death and Disease. 15, 7, 468.Research output: Contribution to journal › Comment/debate
Open Access -
DNA-modified Prussian blue nanozymes for enhanced electrochemical biosensing
Huang, L. H., Hsieh, Y. Y., Yang, F. A. & Liao, W. C., 10 Apr 2024, In: Nanoscale. 16, 20, p. 9770-9780 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Galectin-3 aggravates microglial activation and tau transmission in tauopathy
Siew, J. J., Chen, H. M., Chiu, F. L., Lee, C. W., Chang, Y. M., Chen, H. L., Nguyen, T. N. A., Liao, H. T., Liu, M., Hagar, H. T., Sun, Y. C., Lai, H. L., Kuo, M. H., Blum, D., Buée, L., Jin, L. W., Chen, S. Y., Ko, T. M., Huang, J. R. & Kuo, H. C. & 2 others, , 16 Jan 2024, In: Journal of Clinical Investigation. 134, 2, e165523.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
High-viscosity driven modulation of biomechanical properties of human mesenchymal stem cells promotes osteogenic lineage
Chen, Y. Q., Wu, M. C., Wei, M. T., Kuo, J. C., Yu, H. W. & Chiou, A., Jun 2024, In: Materials Today Bio. 26, 101058.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Human DDX6 regulates translation and decay of inefficiently translated mRNAs
Weber, R. & Chang, C. T., 2024, In: eLife. 13, RP92426.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity
Chiang, W. Y., Yu, H. W., Wu, M. C., Huang, Y. M., Chen, Y. Q., Lin, J. W., Liu, Y. W., You, L. R., Chiou, A. & Kuo, J. C., Jul 2024, In: Biomaterials. 308, 122551.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans
Chen, T. Y., Wang, F. Y., Lee, P. J., Hsu, A. L. & Ching, T. T., Apr 2024, In: Aging Cell. 23, 4, e14103.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations
Tsai, M. H., Ke, H. C., Lin, W. C., Nian, F. S., Huang, C. W., Cheng, H. Y., Hsu, C. S., Granata, T., Chang, C. H., Castellotti, B., Lin, S. Y., Doniselli, F. M., Lu, C. J., Franceschetti, S., Ragona, F., Hou, P. S., Canafoglia, L., Tung, C. Y., Lee, M. H. & Wang, W. J. & 1 others, , Jun 2024, In: Acta Neuropathologica. 147, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Primary cilia formation requires the Leigh syndrome–associated mitochondrial protein NDUFAF2
Lo, C. H., Liu, Z., Chen, S., Lin, F., Berneshawi, A. R., Yu, C. Q., Koo, E. B., Kowal, T. J., Ning, K., Hu, Y., Wang, W. J., Liao, Y. J. & Sun, Y., 1 Jul 2024, In: Journal of Clinical Investigation. 134, 13, e175560.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Regulation of primary cilia disassembly through HUWE1-mediated TTBK2 degradation plays a crucial role in cerebellar development and medulloblastoma growth
Lin, I. H., Li, Y. R., Chang, C. H., Cheng, Y. W., Wang, Y. T., Tsai, Y. S., Lin, P. Y., Kao, C. H., Su, T. Y., Hsu, C. S., Tung, C. Y., Hsu, P. H., Ayrault, O., Chung, B. C., Tsai, J. W. & Wang, W. J., Oct 2024, In: Cell Death and Differentiation. 31, 10, p. 1349-1361 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sarcopenia-related changes in serum GLP-1 level affect myogenic differentiation
Huang, H. H., Wang, Y. J., Jiang, H. Y., Yu, H. W., Chen, Y. Q., Chiou, A. & Kuo, J. C., Oct 2024, In: Journal of Cachexia, Sarcopenia and Muscle. 15, 5, p. 1708-1721 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes
Cheng, I. H., Pi, W. C., Hsu, C. H., Guo, Y., Lai, J. L., Wang, G. G., Chung, B. C., Roeder, R. G. & Chen, W. Y., Dec 2024, In: Cell Death Discovery. 10, 1, 244.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity
Crombie, E. M., Kim, S., Adamson, S., Dong, H., Lu, T. C., Wu, Y., Wu, Y., Levy, Y., Stimple, N., Lam, W. M. R., Hey, H. W. D., Withers, D. J., Hsu, A. L., Bay, B. H., Ochala, J. & Tsai, S. Y., Feb 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, 1, p. 198-213 16 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
AKT2-mediated nuclear deformation leads to genome instability during epithelial-mesenchymal transition
Fan, J. R., Chang, S. N., Chu, C. T. & Chen, H. C., 16 Jun 2023, In: iScience. 26, 6, 106992.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Development of vessel mimicking microfluidic device for studying mechano-response of endothelial cells
Chu, P. Y., Hsieh, H. Y., Chung, P. S., Wang, P. W., Wu, M. C., Chen, Y. Q., Kuo, J. C. & Fan, Y. J., 16 Jun 2023, In: iScience. 26, 6, 106927.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Distinct sets of lysosomal genes define synucleinopathy and Tauopathy
Oh, K. W., Kim, D. K., Hsu, A. L. & Lee, S. J., 2023, In: BMB Reports. 56, 12, p. 657-662 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Early committed polarization of intracellular tension in response to cell shape determines the osteogenic differentiation of mesenchymal stromal cells
Wu, M. C., Yu, H. W., Chen, Y. Q., Ou, M. H., Serrano, R., Huang, G. L., Wang, Y. K., Lin, K. H., Fan, Y. J., Wu, C. C., del Álamo, J. C., Chiou, A., Chien, S. & Kuo, J. C., Jun 2023, In: Acta Biomaterialia. 163, p. 287-301 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Erratum: SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53 (SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53 (2013) 154(2) (297–310), (S0092867413007666), (10.1016/j.cell.2013.06.027))
Tang, Z., Chen, W. Y., Shimada, M., Nguyen, U. T. T., Kim, J., Sun, X. J., Sengoku, T., McGinty, R. K., Fernandez, J. P., Muir, T. W. & Roeder, R. G., 11 May 2023, In: Cell. 186, 10, p. 2280 1 p.Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Ethylene Glycol-Manipulated Syntheses of Calcium Carbonate Particles and DNA Capsules toward Efficient ATP-Responsive Cargo Release
Lin, Y. H., Singuru, M. M. R., Marpaung, D. S. S., Liao, W. C. & Chuang, M. C., 21 Aug 2023, In: ACS Applied Bio Materials. 6, 8, p. 3351-3360 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination
Liu, C. C., Chan, H. R., Su, G. C., Hsieh, Y. Z., Lei, K. H., Kato, T., Yu, T. Y., Kao, Y. W., Cheng, T. H., Chi, P. & Lin, J. J., 22 May 2023, In: Nucleic acids research. 51, 9, p. 4398-4414 17 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Hybridization chain reaction-assisted enzyme cascade genosensor for the detection of Listeria monocytogenes
Yang, F. A., Wu, Y. T., Liu, Y. W. & Liao, W. C., 1 Mar 2023, In: Talanta. 254, 124193.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
IFF: Identifying key residues in intrinsically disordered regions of proteins using machine learning
Ho, W. L., Huang, H. C. & Huang, J. R., Sep 2023, In: Protein Science. 32, 9, e4739.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
INPP5E regulates CD3ζ enrichment at the immune synapse by phosphoinositide distribution control
Chiu, T. Y., Lo, C. H., Lin, Y. H., Lai, Y. D., Lin, S. S., Fang, Y. T., Huang, W. S., Huang, S. Y., Tsai, P. Y., Yang, F. H., Chong, W. M., Wu, Y. C., Tsai, H. C., Liu, Y. W., Hsu, C. L., Liao, J. C. & Wang, W. J., Dec 2023, In: Communications Biology. 6, 1, 911.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Loss of cell-cell adhesion triggers cell migration through Rac1-dependent ROS generation
Chen, Y. H., Hsu, J. Y., Chu, C. T., Chang, Y. W., Fan, J. R., Yang, M.-H. & Chen, H. C., 1 Feb 2023, In: Life Science Alliance. 6, 2Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
Chou, M. C., Wang, Y. H., Chen, F. Y., Kung, C. Y., Wu, K. P., Kuo, J. C., Chan, S. J., Cheng, M. L., Lin, C. Y., Chou, Y. C., Ho, M. C., Firestine, S., Huang, J. R. & Chen, R. H., 16 Nov 2023, In: Molecular Cell. 83, 22, p. 4123-4140.e12Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target
Singh, S., Yeat, N. Y., Wang, Y. T., Lin, S. Y., Kuo, I. Y., Wu, K. P., Wang, W. J., Wang, W. C., Su, W. C., Wang, Y. C. & Chen, R. H., Oct 2023, In: Cell Death and Disease. 14, 10, 671.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Pyruvate kinase M2 modification by a lipid peroxidation byproduct acrolein contributes to kidney fibrosis
Kuo, C. W., Chen, D. H., Tsai, M. T., Lin, C.-C., Cheng, H. W., Tsay, Y. G. & Wang, H.-T., 2023, In: Frontiers in Medicine. 10, 1151359.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity
Lim, C. Y., Lin, H. T., Kumsta, C., Lu, T. C., Wang, F. Y., Kang, Y. H., Hansen, M., Ching, T. T. & Hsu, A. L., 2023, In: Autophagy. 19, 1, p. 224-240 17 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Sequential isolation of metabolites and lipids from a single sample to achieve multiomics by using TRIzol reagent
Kao, C. Y., Chang, C. T., Kuo, P. Y., Lin, C. J., Chiu, H. H. & Liao, H. W., 1 Jun 2023, In: Talanta. 258, 124416.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Smad4-mediated angiogenesis facilitates the beiging of white adipose tissue in mice
Wang, C., Wu, Y., Li, Y., Zhang, Y., Fung, Y. L., Tong, K. K., Lau, C. W., Xiang, L., Kwan, K. M., You, L. R., Huang, Y. & Tian, X. Y., 17 Mar 2023, In: iScience. 26, 3, 106272.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein
Liao, C. C., Wang, Y. S., Pi, W. C., Wang, C. H., Wu, Y. M., Chen, W. Y. & Hsia, K. C., Dec 2023, In: Nature Communications. 14, 1, 5518.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Therapeutic inhibition of ATR in differentiated thyroid cancer
Lin, S. F., Lee, Y. Y., Wu, M. H., Lu, Y. L., Yeh, C. N., Chen, W. Y., Chou, T. C. & Wong, R. J., 2023, In: Endocrine-Related Cancer. 30, 12, e230142.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
Chen, Y. H., Chen, H. H., Wang, W. J., Chen, H. Y., Huang, W. S., Kao, C. H., Lee, S. R., Yeat, N. Y., Yan, R. L., Chan, S. J., Wu, K. P. & Chen, R. H., Dec 2023, In: Nature Communications. 14, 1, 3050.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2022
A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia
Ren, Z., Kim, A., Huang, Y. T., Pi, W. C., Gong, W., Yu, X., Qi, J., Jin, J., Cai, L., Roeder, R. G., Chen, W. Y. & Wang, G. G., 1 Mar 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 9, e2122940119.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
An, Z., Chiang, W. C., Fernández, Á. F., Franco, L. H., He, C. C., Huang, S. Y., Lee, E., Liu, Y., Sebti, S., Shoji-Kawata, S., Sirasanagandla, S., Wang, R. C., Wei, Y., Zhao, Y. & Vega-Rubin-de-Celis, S., 27 Jun 2022, In: Frontiers in Cell and Developmental Biology. 10, 891332.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes
Deng, N., Wu, Y. Y., Feng, Y., Hsieh, W. C., Song, J. S., Lin, Y. S., Tseng, Y. H., Liao, W. J., Chu, Y. F., Liu, Y. C., Chang, E. C., Liu, C. R., Sheu, S. Y., Su, M. T., Kuo, H. C., Cohen, S. N. & Cheng, T. H., 9 Aug 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 32, e2204779119.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Context-specific roles of diphthamide deficiency in hepatocellular carcinogenesis
Tu, W. L., Chih, Y. C., Shih, Y. T., Yu, Y. R., You, L. R. & Chen, C. M., Oct 2022, In: Journal of Pathology. 258, 2, p. 149-163 15 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Development of a traditional Chinese medicine-based agent for the treatment of cancer cachexia
Wu, K. C., Chu, P. C., Cheng, Y. J., Li, C. I., Tian, J., Wu, H. Y., Wu, S. H., Lai, Y. C., Kao, H. H., Hsu, A. L., Lin, H. W. & Lin, C. H., Aug 2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 4, p. 2073-2087 15 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage
Shih, H. T., Chen, W. Y., Wang, H. Y., Chao, T., Huang, H. D., Chou, C. H. & Chang, Z. F., Jun 2022, In: Cell Death and Disease. 13, 6, 546.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
DSIF modulates RNA polymerase II occupancy according to template G + C content
Deng, N., Zhang, Y., Ma, Z., Lin, R., Cheng, T. H., Tang, H., Snyder, M. P. & Cohen, S. N., 1 Sep 2022, In: NAR Genomics and Bioinformatics. 4, 3, lqac054.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of polyallylamine-coated nanoparticles on the optical and photochemical properties of rose bengal
Lin, K. Y., Tsay, Y. G. & Allen Chang, C., 1 Sep 2022, In: Journal of the Chinese Medical Association. 85, 9, p. 901-908 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Engineered multivalent DNA capsules for multiplexed detection of genotoxicants via versatile controlled release mechanisms
Singuru, M. M. R., Liao, Y. C., Lin, G. M. H., Chen, W. T., Lin, Y. H., To, C. T., Liao, W. C., Hsu, C. H. & Chuang, M. C., 15 Nov 2022, In: Biosensors and Bioelectronics. 216, 114608.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Erratum: Structural and Biochemical Characterization of Porcine Epidemic Diarrhea Virus Papain-Like Protease 2 (Journal of Virology (2022) 96:1 (e01372-21) DOI: 10.1128/JVI.01372-21)
Chu, H. F., Cheng, S. C., Sun, C. Y., Chou, C. Y., Lin, T.-H. & Chen, W. Y., Mar 2022, In: Journal of Virology. 96, 6, e00091-22.Research output: Contribution to journal › Comment/debate
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EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
Wang, J., Yu, X., Gong, W., Liu, X., Park, K. S., Ma, A., Tsai, Y. H., Shen, Y., Onikubo, T., Pi, W. C., Allison, D. F., Liu, J., Chen, W. Y., Cai, L., Roeder, R. G., Jin, J. & Wang, G. G., Mar 2022, In: Nature Cell Biology. 24, 3, p. 384-399 16 p.Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
Mitophagy in aging and longevity
Guo, J. & Chiang, W. C., Apr 2022, In: IUBMB Life. 74, 4, p. 296-316 21 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction
Dong, X., Liang, Q., Pan, Y. Z., Wang, X., Kuo, Y. C., Chiang, W. C., Zhang, X., Williams, N. S., Rizo, J., Levine, B. & De Brabander, J. K., 8 Sep 2022, In: ACS Medicinal Chemistry Letters. 13, 9, p. 1510-1516 7 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Persistent TLR4 Activation Promotes Hepatocellular Carcinoma Growth through Positive Feedback Regulation by LIN28A/Let-7g miRNA
Chen, I. T., Cheng, A. C., Liu, Y. T., Yan, C., Cheng, Y. C., Chang, C. F. & Tseng, P. H., Aug 2022, In: International Journal Of Molecular Sciences. 23, 15, 8419.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Phase separation driven by interchangeable properties in the intrinsically disordered regions of protein paralogs
Chiu, S. H., Ho, W. L., Sun, Y. C., Kuo, J. C. & Huang, J. R., Dec 2022, In: Communications Biology. 5, 1, 400.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations