Department of Biological Science and Technology

2025

Regulation of PD-L1 glycosylation and advances in cancer immunotherapy

Lee, T. A., Tsai, E. Y., Liu, S. H., Chou, W. C., Hsu Hung, S. D., Chang, C. Y., Chao, C. H., Yamaguchi, H., Lai, Y. J., Chen, H. L. & Li, C. W., 1 Mar 2025, In: Cancer Letters. 612, 217498.

Research output: Contribution to journal › Review article › peer-review

Open Access

2024

Post-translational Modification of PD-1: Potential Targets for Cancer Immunotherapy

Lee, T. A., Tsai, E. Y., Liu, S. H., Hung, S. D. H., Chang, S. J., Chao, C. H., Lai, Y. J., Yamaguchi, H. & Li, C. W., 15 Mar 2024, In: Cancer Research. 84, 6, p. 800-807 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

Prevalence of environmental microplastics in Taiwan and its impact on the seafood safety: An integrative review

Lin, M. W., Wu, V. C. H. & Lin, C. S., Jun 2024, In: Journal of Food Safety. 44, 3, e13148.

Research output: Contribution to journal › Review article › peer-review

2023

Nature-Inspired Surface Structures Design for Antimicrobial Applications

Lee, M. S., Hussein, H. R., Chang, S. W., Chang, C. Y., Lin, Y. Y., Chien, Y., Yang, Y. P., Kiew, L. V., Chen, C. Y., Chiou, S. H. & Chang, C. C., Jan 2023, In: International Journal Of Molecular Sciences. 24, 2, 1348.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Scopus citations

2022

Advances, applications, and limitations of portable and rapid detection technologies for routinely encountered foodborne pathogens

Quintela, I. A., Vasse, T., Lin, C. S. & Wu, V. C. H., 5 Dec 2022, In: Frontiers in Microbiology. 13, 1054782.

Research output: Contribution to journal › Review article › peer-review

Open Access

22 Scopus citations

Glucuronides: From biological waste to bio-nanomedical applications

Burnouf, P. A., Roffler, S. R., Wu, C. C. & Yu-Cheng, S., Sep 2022, In: Journal of Controlled Release. 349, p. 765-782 18 p.

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Meta-analytic evidence for the cognitive control model of loneliness in emotion processing

Wong, N. M. L., Mabel-Kenzie, S. T. S. T., Lin, C., Huang, C. M., Liu, H. L., Lee, S. H. & Lee, T. M. C., Jul 2022, In: Neuroscience and Biobehavioral Reviews. 138, p. 104686 1 p., 104686.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

p53-Mediated Indirect Regulation on Cellular Metabolism: From the Mechanism of Pathogenesis to the Development of Cancer Therapeutics

Wang, C. Y. & Chao, C. H., 30 May 2022, In: Frontiers in Oncology. 12, 895112.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

2021

A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays

Sun, T. H., Shao, Y. H. J., Mao, C. L., Hung, M. N., Lo, Y. Y., Ko, T.-M. & Hsiao, T. H., 26 Oct 2021, In: Frontiers in Genetics. 12, p. 1-8 8 p., 736390.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

A review of epidemic investigation on cold-chain food-mediated SARS-CoV-2 transmission and food safety consideration during COVID-19 pandemic

Lu, L. C., Quintela, I., Lin, C. H., Lin, T. C., Lin, C. H., Wu, V. C. H. & Lin, C. S., Dec 2021, In: Journal of Food Safety. 41, 6, e12932.

Research output: Contribution to journal › Review article › peer-review

Open Access

29 Scopus citations

Cultivation and biorefinery of microalgae (Chlorella sp.) for producing biofuels and other byproducts: A review

Kuo, C. M., Sun, Y. L., Lin, C. H., Lin, C. H., Wu, H. T. & Lin, C. S., 1 Dec 2021, In: Sustainability (Switzerland). 13, 23, 13480.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

MUT-7 provides molecular insight into the werner syndrome exonuclease

Hsu, T. Y., Hsu, L. N., Chen, S. Y. & Juang, B. T., Dec 2021, In: Cells. 10, 12, 3457.

Research output: Contribution to journal › Review article › peer-review

Open Access

Resolution of a vocal fold polyp treated with Chinese herbal medicine: One case report with literature review

Chang, C.-H., Lin, C.-P., MacDonald, I., Chiu, T.-W. & Huang, S.-T., Oct 2021, In: Journal of Herbal Medicine. 29, 6 p., 100486.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Review of recent advances in improved lateral flow immunoassay for the detection of pathogenic Escherichia coli O157:H7 in foods

Sun, Y. L., Kuo, C. M., Lu, C. L. & Lin, C. S., Feb 2021, In: Journal of Food Safety. 41, 1, e12867.

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

The impact of phthalate on reproductive function in women with endometriosis

Chou, Y.-C. & Tzeng, C. R., 5 Apr 2021, In: Reproductive Medicine and Biology. 20, 2, p. 159–168 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

The influence of dataset homology and a rigorous evaluation strategy on protein secondary structure prediction

Chen, T. R., Lo, C. H., Juan, S. H. & Lo, W. C., Jul 2021, In: PLoS ONE. 16, 7 July, e0254555.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

2020

Chemical Production from Methanol Using Natural and Synthetic Methylotrophs

Chen, A. Y. & Lan, E. I., Apr 2020, (Accepted/In press) In: Biotechnology Journal. 14 p., 1900356.

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Metabolic engineering design strategies for increasing acetyl-coa flux

Ku, J. T., Chen, A. Y. & Lan, E. I., Apr 2020, In: Metabolites. 10, 4, 166.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Scopus citations

Terpene synthases in disguise: Enzymology, structure, and opportunities of non-canonical terpene synthases

Rudolf, J. D. & Chang, C.-Y., 1 Mar 2020, In: Natural Product Reports. 37, 3, p. 425-463 39 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

101 Scopus citations

Ultrasound in tumor immunotherapy: Current status and future developments

Ho, Y. J., Li, J. P., Fan, C. H., Liu, H. L. & Yeh, C. K., 10 Jul 2020, In: Journal of Controlled Release. 323, p. 12-23 12 p.

Research output: Contribution to journal › Review article › peer-review

70 Scopus citations

2019

The fabrication and application of Ni-DNA nanowire-based nanoelectronic devices

Chang, P. C., Chang, C. Y., Jian, W.-B., Yuan, C.-J., Chen, Y.-C. & Chang, C.-C., Jun 2019, In: Nano Research. 12, 6, p. 1293–1300 8 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

2018

Escherichia coli as a host for metabolic engineering

Pontrelli, S., Chiu, T. Y., Lan, E. I., Chen, F. Y. H., Chang, P. & Liao, J. C., Nov 2018, In: Metabolic Engineering. 50, p. 16-46 31 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

292 Scopus citations

In vitro and in vivo experimental studies of PM _2.5 on disease progression

Cho, C. C., Hsieh, W. Y., Tsai, C. H., Chen, C. Y., Chang, H. F. & Lin, C.-S., 1 Jul 2018, In: International journal of environmental research and public health. 15, 7, 1380.

Research output: Contribution to journal › Review article › peer-review

Open Access

164 Scopus citations

2017

Alkali metal ion-enhanced threading of a perylenediimidebound polymer chain through a double-stranded spiroborate helicate with a bisporphyrin unit

Ousaka, N., Yamamoto, S., Hayashi, N., Li, M.-C., Ho, R. M. & Yashima, E., 1 Jan 2017, In: Chemistry Letters. 46, 7, p. 970-972 3 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Current progress in antivascular tumor therapy

Ho, Y.-J., Wang, T. C., Fan, C. H. & Yeh, C. K., Oct 2017, In: Drug Discovery Today. 22, 10, p. 1503-1515 13 p.

Research output: Contribution to journal › Review article › peer-review

46 Scopus citations

Cytochromes P450 for natural product biosynthesis in: Streptomyces: sequence, structure, and function

Rudolf, J. D., Chang, C.-Y., Ma, M. & Shen, B., Sep 2017, In: Natural Product Reports. 34, 9, p. 1141-1172 32 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

163 Scopus citations

DNA-based nanowires and nanodevices

Ram Kumar Pandian, S., Yuan, C.-J., Lin, C. C., Wang, W. H. & Chang, C.-C., 2017, In: Advances in Physics: X. 2, 1, p. 22-34 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

Therapeutic hypothermia for neonates with hypoxic ischemic encephalopathy

Chiang, M. C., Jong, Y.-J. & Lin, C.-H., Dec 2017, In: Pediatrics and Neonatology. p. 475-483 9 p.

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

2016

Pharmacogenomics for personalized pain medicine

Ko, T.-M., Wong, C. S., Wu, J. Y. & Chen, Y. T., 1 Mar 2016, In: Acta Anaesthesiologica Taiwanica. 54, 1, p. 24-30 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

21 Scopus citations

Single-incision laparoscopic surgery for biliary tract disease

Chuang, S. H. & Lin, C.-S., 14 Jan 2016, In: World Journal of Gastroenterology. 22, 2, p. 736-747 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

19 Scopus citations

2015

Advances in metabolic engineering of cyanobacteria for photosynthetic biochemical production

Lai, M. C. & Lan, E. I., 27 Oct 2015, In: Metabolites. 5, 4, p. 636-658 23 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

82 Scopus citations

Cultivation of microalgal Chlorella for biomass and lipid production using wastewater as nutrient resource

Chiu, S. Y., Kao, C. Y., Chen, T. Y., Chang, Y. B., Kuo, C. M. & Lin, C.-S., 1 May 2015, In: Bioresource Technology. 184, p. 179-189 11 p.

Research output: Contribution to journal › Review article › peer-review

304 Scopus citations

Mechanism of sulfotransferase pharmacogenetics in altered xenobiotic metabolism

Chen, B. H., Wang, C. C., Hou, Y. H., Mao, Y. C. & Yang, Y.-S., 1 Jul 2015, In: Expert Opinion on Drug Metabolism and Toxicology. 11, 7, p. 1053-1071 19 p.

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

2014

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

Shih, J. W. & Wu Lee, Y.-H., 25 Sep 2014, In: Clinica Chimica Acta. 436, p. 45-58 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

30 Scopus citations

2013

Efficacy and practical issues of repetitive transcranial magnetic stimulation on chronic medically unexplained symptoms of pain

Li, C. T., Su, T. P., Hsieh, J. C. & Ho, S. T., Jun 2013, In: Acta Anaesthesiologica Taiwanica. 51, 2, p. 81-87 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Targeting cancer stem cells: Emerging role of Nanog transcription factor

Wang, M. L., Chiou, S. H. & Wu Lee, C.-W., 19 Sep 2013, In: OncoTargets and Therapy. 6, p. 1207-1220 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

150 Scopus citations

2012

A recent update of pharmacogenomics in drug-induced severe skin reactions

Wei, C. Y., Ko, T.-M., Shen, C. Y. & Chen, Y. T., 2012, In: Drug Metabolism and Pharmacokinetics. 27, 1, p. 132-141 10 p.

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

K63-linked ubiquitination in kinase activation and cancer

Wang, G., Gao, Y., Li, L., Jin, G., Cai, Z., Chao, J.-I. & Lin, H. K., 1 Dec 2012, In: Frontiers in Oncology. 2, JAN, 00005.

Research output: Contribution to journal › Review article › peer-review

Open Access

86 Scopus citations

Non-viral delivery of RNA interference targeting cancer cells in cancer gene therapy

Huang, P. I., Lo, W. L., Cherng, J. Y., Chien, Y., Chiou, G.-Y. & Chiou, S. H., 2012, In: Current Gene Therapy. 12, 4, p. 275-284 10 p.

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: Understanding a hypersensitivity reaction

Ko, T.-M. & Chen, Y. T., 1 Jul 2012, In: Expert Review of Clinical Immunology. 8, 5, p. 467-477 11 p.

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

2011

On the Relationship Between Catalytic Residues and their Protein Contact Number

Huang, S.-W., Yu, S.-H., Shih, C. H., Guan, H.-W., Huang, T.-T. & Hwang, J.-K., Sep 2011, In: CURRENT PROTEIN & PEPTIDE SCIENCE. 12, 6, p. 574-579 6 p.

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

The relevance of protein-ligand interaction profiles in computer-aided novel compound design and applications

Clinciu, D. L., Yang, J.-M., Hsu, K. C., Lo, C. C., Wallace, S. & Yu, H. C., Sep 2011, In: Current Bioinformatics. 6, 3, p. 383-388 6 p.

Research output: Contribution to journal › Review article › peer-review

2010

Birth time/order-dependent neuron type specification

Kao, C. F. & Lee, T., Feb 2010, In: Current Opinion in Neurobiology. 20, 1, p. 14-21 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

Culture wires the Brain: A cognitive neuroscience perspective

Park, D. C. & Huang, C.-M., Jul 2010, In: Perspectives on Psychological Science. 5, 4, p. 391-400 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

167 Scopus citations

Drowsiness monitoring with EEG-based MEMS biosensing technologies

Chang, C. W., Ko, L.-W., Lin, F. C., Su, T. P., Jung, T. P., Lin, C. T. & Chiou, J.-C., 2010, In: GeroPsych: The Journal of Gerontopsychology and Geriatric Psychiatry. 23, 2, p. 107-113 7 p.

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

From sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function

Hsu, C. C., Lu, L. Y. & Yang, Y.-S., 1 May 2010, In: Expert Opinion on Drug Metabolism and Toxicology. 6, 5, p. 591-601 11 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Leiomyoma and Vascular Endothelial Growth Factor Gene Polymorphisms: A Systematic Review

Chang, C. C., Hsieh, Y. Y., Lin, W. H. & Lin, C.-S., 1 Sep 2010, In: Taiwanese Journal of Obstetrics and Gynecology. 49, 3, p. 247-253 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

MicroRNA and aging: A novel modulator in regulating the aging network

Chen, L. H., Chiou, G.-Y., Chen, Y. W., Li, H. Y. & Chiou, S. H., 1 Nov 2010, In: Ageing Research Reviews. 9, SUPPL.

Research output: Contribution to journal › Review article › peer-review

103 Scopus citations

Review of wireless and wearable electroencephalogram systems and brain-computer interfaces - A mini-review

Lin, C.-T., Ko, L.-W., Chang, M. H., Duann, J.-R., Chen, J. Y., Su, T. P. & Jung, T. P., 1 Jan 2010, In: Gerontology. 56, 1, p. 112-119 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

108 Scopus citations

2008

Biosignaling of mammalian Ste20-related kinases

Ling, P., Lu, T. J., Yuan, C.-J. & Lai, M. D., 1 Jul 2008, In: Cellular Signalling. 20, 7, p. 1237-1247 11 p.

Research output: Contribution to journal › Review article › peer-review

118 Scopus citations

Department of Biological Science and Technology

Research output

Search results